Dysregulation of systemic soluble immune checkpoints in early breast cancer is attenuated following administration of neoadjuvant chemotherapy and is associated with recovery of CD27, CD28, CD40, CD80, ICOS and GITR and substantially increased levels of PD-L1, LAG-3 and TIM-3
早期乳腺癌中系统性可溶性免疫检查点的失调在接受新辅助化疗后得到缓解，并与CD27、CD28、CD40、CD80、ICOS和GITR的恢复以及PD-L1、LAG-3和TIM-3水平的显著升高相关。
期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2023.1097309
Rapoport, Bernardo L; Steel, Helen C; Benn, Carol A; Nayler, Simon; Smit, Teresa; Heyman, Liezl; Theron, Annette J; Hlatshwayo, Nomsa; Kwofie, Luyanda L I; Meyer, Pieter W A; Anderson, Ronald
肿瘤
T细胞
TIM
肿瘤免疫
ICOS
乳腺癌
CD8
CD80
CD40
PD-L1
CD27
CD2
CD28
CD4
免疫/内分泌
