日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Acute kidney injury in severe alcohol-associated hepatitis treated with anakinra plus zinc or prednisone.

严重酒精相关性肝炎患者接受阿那白滞素加锌或泼尼松治疗后出现急性肾损伤

期刊:Hepatology
影响因子:15.8
doi:10.1097/HEP.0000000000001019
Patidar Kavish R, Tu Wanzhu, Cotter Thomas G, Simonetto Douglas A, Asgharpour Amon, Jan Muhammad Y, Tang Qing, Yu Yunpeng, Li Yang, Taiwo Moyinoluwa, Thevkar Nagesh Prashanth, Dasarathy Srinivasan, Kamath Patrick S, McClain Craig J, Chalasani Naga, Szabo Gyongyi, Bataller Ramon, Mitchell Mack, Mehal Wajahat Z, Nagy Laura E, Shah Vijay H, Gawrieh Samer, Sanyal Arun J
炎症/感染
肝炎
肾损伤
炎症
发表日期：2025
文献求助 收藏

Transcriptome of monocytes from liver, brain and bone marrow reveals organ-specific features in aging and alcohol misuse

肝脏、大脑和骨髓单核细胞的转录组揭示了衰老和酒精滥用中的器官特异性特征

期刊:Jhep Reports
影响因子:9.5
doi:10.1016/j.jhepr.2025.101603
Martí Ortega-Ribera ，Radhika Joshi ，Sergi Guixé-Muntet ，Veronika Brezani ，Prashanth Thevkar Nagesh ，Viliam Brezani ，Arman Patel ，Yuan Zhuang ，Mrigya Babuta ，Jordi Gracia-Sancho ，Gyongyi Szabo
神经科学
发表日期：2025
文献求助 收藏

Ethanol consumption aggravates amyloid pathology and neuroinflammation in Alzheimer's disease associated with inflammasome activation and ASC speck propagation

乙醇摄入会加剧阿尔茨海默病中的淀粉样蛋白病理和神经炎症，这与炎症小体激活和ASC斑点扩散有关。

期刊:Journal of Neuroinflammation
影响因子:9.3
doi:10.1186/s12974-025-03501-8
Veronika Brezani ，Radhika S Joshi ，Marti Ortega-Ribera ，Prashanth Thevkar Nagesh ，Viliam Brezani ，Adam Zivny ，Evelyn A Kurt-Jones ，Douglas T Golenbock ，Gyongyi Szabo
ASC
炎性小体
炎症/感染
炎性小体
神经炎症
阿尔茨海默症
神经科学
炎症
免疫/内分泌
发表日期：2025
文献求助 收藏

A Novel Multi-organ Male Model of Alcohol-induced Acute-on-chronic Liver Failure Reveals NET-mediated Hepatocellular Death, Which is Prevented by RIPK3 Inhibition

一种新型多器官雄性酒精性急性加慢性肝衰竭模型揭示了NET介导的肝细胞死亡，而RIPK3抑制剂可阻止这种死亡。

期刊:Cellular and Molecular Gastroenterology and Hepatology
影响因子:7.1
doi:10.1016/j.jcmgh.2024.101446
Martí Ortega-Ribera ，Yuan Zhuang ，Mrigya Babuta ，Veronika Brezani ，Radhika S Joshi ，Zsuzsanna Zsengeller ，Prashanth Thevkar Nagesh ，Yanbo Wang ，Roderick Bronson ，Gyongyi Szabo
细胞生物学
RIPK3
肝衰竭
RIP
毒理研究
发表日期：2025
文献求助 收藏

Gasdermin D deletion prevents liver injury and exacerbates extrahepatic damage in a murine model of alcohol-induced ACLF.

Gasdermin D 缺失可预防酒精性急性肝衰竭小鼠模型中的肝损伤，并加剧肝外损伤

期刊:
影响因子:
doi:10.1136/egastro-2024-100151
Ortega-Ribera Martí, Zhuang Yuan, Brezani Veronika, Joshi Radhika S, Zsengeller Zsuzsanna, Nagesh Prashanth Thevkar, Datta Aditi, Szabo Gyongyi
毒理研究
肝损伤
发表日期：2025
文献求助 收藏

Neutrophil extracellular traps activate hepatic stellate cells and monocytes via NLRP3 sensing in alcohol-induced acceleration of MASH fibrosis

中性粒细胞胞外陷阱通过NLRP3感应激活肝星状细胞和单核细胞，从而加速酒精诱导的MASH纤维化。

期刊:Gut
影响因子:25.8
doi:10.1136/gutjnl-2023-331447
Babuta, Mrigya; Morel, Caroline; de Carvalho Ribeiro, Marcelle; Calenda, Charles; Ortega-Ribera, Martí; Thevkar Nagesh, Prashanth; Copeland, Christopher; Zhuang, Yuan; Wang, Yanbo; Cho, Yeonhee; Joshi, Radhika; Brezani, Viliam; Hawryluk, Danielle; Datta, Aditi Ashish; Mehta, Jeeval; Nasser, Imad; Szabo, Gyongyi
中性粒细胞
粒细胞
LRP3
单核细胞
NLRP3
细胞生物学
发表日期：2024
文献求助 收藏

Bile acid-induced IRF3 phosphorylation mediates cell death, inflammatory responses, and fibrosis in cholestasis-induced liver and kidney injury via regulation of ZBP1

胆汁酸诱导的IRF3磷酸化通过调节ZBP1介导胆汁淤积引起的肝肾损伤中的细胞死亡、炎症反应和纤维化。

期刊:Hepatology
影响因子:15.8
doi:10.1097/HEP.0000000000000611
Zhuang, Yuan; Ortega-Ribera, Martí; Thevkar Nagesh, Prashanth; Joshi, Radhika; Huang, Huihui; Wang, Yanbo; Zivny, Adam; Mehta, Jeeval; Parikh, Samir M; Szabo, Gyongyi
IRF3
炎症
炎症/感染
信号转导
ZBP1
肾损伤
磷酸化
细胞生物学
毒理研究
发表日期：2024
文献求助 收藏

In vivo Bruton's tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis

体内布鲁顿酪氨酸激酶抑制剂通过调节CD84介导的粒细胞生成来减轻酒精相关性肝病

期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.adg1915
Nagesh, Prashanth Thevkar; Cho, Yeonhee; Zhuang, Yuan; Babuta, Mrigya; Ortega-Ribera, Marti; Joshi, Radhika; Brezani, Veronika; Patel, Arman; Datta, Aditi Ashish; Brezani, Viliam; Hsieh, Yun-Cheng; Ramos, Adriana; Mehta, Jeeval; Copeland, Christopher; Kanata, Eleni; Jiang, Zhenghui Gordon; Vlachos, Ioannis; Asara, John; Szabo, Gyongyi
T细胞
信号转导
CD8
粒细胞
CD84
细胞生物学
发表日期：2024
文献求助 收藏

Combined Insults of a MASH Diet and Alcohol Binges Activate Intercellular Communication and Neutrophil Recruitment via the NLRP3-IL-1β Axis in the Liver

MASH饮食和酒精暴饮的联合作用会通过肝脏中的NLRP3-IL-1β轴激活细胞间通讯和中性粒细胞募集

期刊:Cells
影响因子:5.1
doi:10.3390/cells13110960
Mrigya Babuta ，Prashanth Thevkar Nagesh ，Aditi Ashish Datta ，Victoria Remotti ，Yuan Zhuang ，Jeeval Mehta ，Francesca Lami ，Yanbo Wang ，Gyongyi Szabo
中性粒细胞
NLRP3
粒细胞
细胞生物学
LRP3
IL-1β
发表日期：2024
文献求助 收藏

G-CSF increases calprotectin expression, liver damage and neuroinflammation in a murine model of alcohol-induced ACLF

在酒精诱导的急性肝衰竭小鼠模型中，G-CSF 可增加钙卫蛋白表达、肝损伤和神经炎症。

期刊:Frontiers in Cell and Developmental Biology
影响因子:4.6
doi:10.3389/fcell.2024.1347395
Martí Ortega-Ribera ，Yuan Zhuang ，Veronika Brezani ，Prashanth Thevkar Nagesh ，Radhika S Joshi ，Mrigya Babuta ，Yanbo Wang ，Gyongyi Szabo
肝衰竭
炎症/感染
G-CSF
肝损伤
毒理研究
神经科学
神经炎症
炎症
发表日期：2024
文献求助 收藏