日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Proton-selective conductance and gating of the lysosomal cation channel TMEM175

溶酶体阳离子通道TMEM175的质子选择性电导和门控

Schulze, Tobias; Sprave, Timon; Groebe, Carolin; Hendrik Krumbach, Jan; Behringer, Magnus; Bazzone, Andre; Zerlotti, Rocco; Fertig, Niels; Althaus, Mike; Hamacher, Kay; Thiel, Gerhard; Grimm, Christian; Rauh, Oliver

AMPK-mediated HCN4 channel phosphorylation contributes to age-related intrinsic bradycardia

AMPK介导的HCN4通道磷酸化导致与年龄相关的内在性心动过缓

Palloni, Luca M G; Sarno, Nicole; Azzoni, Caterina; Furia, Nicol; Mangoni, Matteo E; Porro, Alessandro; Neeman, Teresa; Saponaro, Andrea; Thiel, Gerhard; Moroni, Anna; DiFrancesco, Dario

Comprehensive classification of HCN1 variants linked to neurodevelopmental disorders with and without epilepsy

对与伴有或不伴有癫痫的神经发育障碍相关的HCN1变异体进行全面分类

Castelli, Roberta; Marini, Carla; Porro, Alessandro; Castellini, Anna; Fontana, Greta; Saponaro, Andrea; Cavalleri, Gianpiero; Rizzi, Susanna; Fusco, Carlo; Parida, Amitav; Caswell, Richard; Sherlaw, Charlotte; Pruna, Dario; Reid, Chris; Bleakley, Lauren E; Howell, Katherine B; Sheffer, Ingrid; Cuddapah, Vishnu Anad; Zeidler, Shimriet; Pavlidis, Elena; Pal, Deb; Szczałuba, Krzysztof; Mirzaa, Ghayda; Couque, Nathalie; Capri, Yline; Faivre, Laurence; Mau-Them, Frederic Tran; Sirchia, Fabio; Korff, Christian M; DiFrancesco, Dario; Thiel, Gerhard; Depienne, Christel; Santoro, Bina; Moroni, Anna

Extracellular activation of HCN4 by a subtype-specific nanobody

亚型特异性纳米抗体对HCN4的细胞外激活

Sharifzadeh, Atiyeh Sadat; Castelli, Roberta; Porro, Alessandro; Mesirca, Pietro; Perrier, Romain; Gómez, Ana M; Mekrane, Nadia; Benoit, Hugo; Meli, Albano C; Palloni, Luca M G; DiFrancesco, Dario; Mangoni, Matteo E; Thiel, Gerhard; Saponaro, Andrea; Moroni, Anna

Modular architecture of K(+) channels: the functional plasticity of the pore module

钾离子通道的模块化结构:孔道模块的功能可塑性

Rauh, Oliver; Schulze, Tobias; Van Etten, James L; Thiel, Gerhard; Moroni, Anna

Unraveling pH Regulation of TMEM175, an Endolysosomal Cation Channel With a Role in Parkinson's Disease

揭示TMEM175的pH调控机制,TMEM175是一种内溶酶体阳离子通道,在帕金森病中发挥作用

Schulze, Tobias; Rauh, Oliver; Thiel, Gerhard; Fertig, Niels; Bazzone, Andre; Grimm, Christian

Differentiation and functionality of human bronchial epithelial cells in an air-liquid interface culture are modified by irradiation exposure

辐射照射会改变气液界面培养中人支气管上皮细胞的分化和功能。

Röder, Kim; Lerchl, Sylvie; Eilenstein, David; Hartel, Carola; Schroeder, Insa S; Thiel, Gerhard; Scholz, Michael; Fournier, Claudia

Yeast complementation assays provide limited information on functional features of K(+) channels

酵母互补试验对钾离子通道的功能特征提供的信息有限。

Kukovetz, Kerri; Cartolano, Matea; Gebhardt, Manuela; Schumann, Lars E; Kast, Stefan M; Moroni, Anna; Thiel, Gerhard; Rauh, Oliver

Anisotropic Network Analysis of Open/Closed HCN4 Channel Advocates Asymmetric Subunit Cooperativity in cAMP Modulation of Gating

各向异性网络分析表明,HCN4通道开放/关闭状态下,亚基间存在不对称的协同作用,这体现在cAMP对通道门控的调节中。

Kunzmann, Patrick; Krumbach, Jan H; Saponaro, Andrea; Moroni, Anna; Thiel, Gerhard; Hamacher, Kay

Mutation in pore-helix modulates interplay between filter gate and Ba2+ block in a Kcv channel pore

孔道螺旋的突变调节Kcv通道孔中过滤门和Ba2+阻滞之间的相互作用

Tewes, Noel; Kubitzki, Beatrice; Bytyqi, Flandrit; Metko, Nikola; Mach, Sebastian; Thiel, Gerhard; Rauh, Oliver