日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting miR-497-5p rescues human keratinocyte dysfunction upon skin exposure to sulfur mustard

靶向 miR-497-5p 可挽救皮肤暴露于芥子气后的人类角质形成细胞功能障碍

Virginia Egea, Karina Lutterberg, Dirk Steinritz, Simone Rothmiller, Konrad Steinestel, Jan Caca, Andreas Nerlich, Helmut Blum, Sarah Reschke, Sajjad Khani, Alexander Bartelt, Franz Worek, Horst Thiermann, Christian Weber, Christian Ries1

The blistering warfare agent O-mustard (agent T) generates protein-adducts with human serum albumin useful for biomedical verification of exposure and forms intramolecular cross-links

灼热战毒剂 O 芥子气(T 毒剂)与人血清白蛋白生成蛋白质加合物,可用于生物医学验证暴露情况,并形成分子内交联

Marc-Michael Blum, Wolfgang Schmeißer, Marina Dentzel, Horst Thiermann, Harald John

Evidence of nerve agent VX exposure in rat plasma by detection of albumin-adducts in vitro and in vivo

通过体外和体内检测白蛋白加合物证明大鼠血浆中 VX 神经毒剂的暴露情况

Tamara Kranawetvogl, Andreas Kranawetvogl, Lisa Scheidegger, Timo Wille, Dirk Steinritz, Franz Worek, Horst Thiermann, Harald John

Isolation of human TRPA1 channel from transfected HEK293 cells and identification of alkylation sites after sulfur mustard exposure

从转染的 HEK293 细胞中分离人类 TRPA1 通道并鉴定芥子气暴露后的烷基化位点

Katharina Müller-Dott, Horst Thiermann, Harald John, Dirk Steinritz

Highly stable peptide adducts from hard keratins as biomarkers to verify local sulfur mustard exposure of hair by high-resolution mass spectrometry

硬角蛋白中高度稳定的肽加合物作为生物标记物,通过高分辨率质谱法验证头发局部芥子气暴露

Wolfgang Schmeißer, Markus Siegert, Horst Thiermann, Theo Rein, Harald John

Sulfur mustard single-dose exposure triggers senescence in primary human dermal fibroblasts

单剂量硫芥暴露可引发人类原代真皮成纤维细胞衰老

Gabriele Horn #, Catherine Schäfers #, Horst Thiermann, Sandra Völkl, Annette Schmidt, Simone Rothmiller

Post-VX exposure treatment of rats with engineered phosphotriesterases

使用工程磷酸三酯酶对大鼠进行 VX 暴露后治疗

Lisa Stigler, Anja Köhler, Marianne Koller, Laura Job, Benjamin Escher, Heidrun Potschka, Horst Thiermann, Arne Skerra, Franz Worek, Timo Wille

Organophosphorus pesticides exhibit compound specific effects in rat precision-cut lung slices (PCLS): mechanisms involved in airway response, cytotoxicity, inflammatory activation and antioxidative defense

有机磷农药在大鼠精密切割肺切片 (PCLS) 中表现出化合物特异性效应:涉及气道反应、细胞毒性、炎症激活和抗氧化防御的机制

Jonas Tigges, Franz Worek, Horst Thiermann, Timo Wille

The Efficiency of Direct Maturation: the Comparison of Two hiPSC Differentiation Approaches into Motor Neurons

直接成熟效率:两种hiPSC分化为运动神经元方法的比较

Catherine Schaefers ,Simone Rothmiller ,Horst Thiermann ,Theo Rein ,Annette Schmidt

Transthyretin as a target of alkylation and a potential biomarker for sulfur mustard poisoning: Electrophoretic and mass spectrometric identification and characterization

转甲状腺素蛋白作为烷基化的靶点和芥子气中毒的潜在生物标志物:电泳和质谱鉴定和表征

Wolfgang Schmeißer, Robin Lüling, Dirk Steinritz, Horst Thiermann, Theo Rein, Harald John