日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

12/15-lipoxygenase orchestrates murine wound healing via PPARγ-activating oxylipins acting holistically to dampen inflammation

12/15-脂氧合酶通过激活PPARγ的氧化脂质来协调小鼠伤口愈合，其作用机制是整体抑制炎症反应。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2502640122
Thomas, Christopher P; Tyrrell, Victoria J; Burston, James J; Johnson, Sam R C; Aldrovandi, Maceler; Alvarez-Jarreta, Jorge; Inglis, Rossa; Leonard, Adam; Fice, Lydia; Costales, Jeremie; Vidal-Puig, Antonio; Protty, Majd; Guy, Carol; Andrews, Robert; Szomolay, Barbara; Cossins, Ben C; Cardus Figueras, Ana; Carobbio, Stefania; Jones, Simon A; O'Donnell, Valerie B
炎症/感染
氧化脂质
炎症
发表日期：2025
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Identification of harmine and β-carboline analogs from a high-throughput screen of an approved drug collection; profiling as differential inhibitors of DYRK1A and monoamine oxidase A and for in vitro and in vivo anti-cancer studies

从已批准药物库的高通量筛选中鉴定哈尔明和β-咔啉类似物；分析其作为DYRK1A和单胺氧化酶A差异性抑制剂的特性，并用于体外和体内抗癌研究。

期刊:European Journal of Pharmaceutical Sciences
影响因子:4.3
doi:10.1016/j.ejps.2021.105821
Michael Tarpley ,Helen O Oladapo ,Dillon Strepay ,Thomas B Caligan ,Lhoucine Chdid ,Hassan Shehata ,Jose R Roques ,Rhashad Thomas ,Christopher P Laudeman ,Rob U Onyenwoke ,David B Darr ,Kevin P Williams
DYR
DYRK1A
肿瘤免疫
肿瘤
发表日期：2021
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Lipidomic and transcriptional analysis of the linoleoyl-omega-hydroxyceramide biosynthetic pathway in human psoriatic lesions

人银屑病皮损中亚油酰-ω-羟基神经酰胺生物合成途径的脂质组学和转录组学分析

期刊:Journal of Lipid Research
影响因子:4.1
doi:10.1016/j.jlr.2021.100094
Tyrrell, Victoria J; Ali, Faraz; Boeglin, William E; Andrews, Robert; Burston, James; Birchall, James C; Ingram, John R; Murphy, Robert C; Piguet, Vincent; Brash, Alan R; O'Donnell, Valerie B; Thomas, Christopher P
银屑病
发表日期：2021
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A novel role for 12/15-lipoxygenase in regulating autophagy.

12/15-脂氧合酶在调节自噬中的新作用

期刊:Redox Biology
影响因子:11.9
doi:10.1016/j.redox.2014.11.005
Morgan Alwena H, Hammond Victoria J, Sakoh-Nakatogawa Machiko, Ohsumi Yoshinori, Thomas Christopher P, Blanchet Fabien, Piguet Vincent, Kiselyov Kirill, O'Donnell Valerie B
免疫/内分泌
自噬
发表日期：2015
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The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier

脂氧合酶-己氧素通路在哺乳动物表皮屏障中的重要性

期刊:
影响因子:
doi:10.1016/j.bbalip.2013.08.020
Muñoz-Garcia, Agustí; Thomas, Christopher P; Keeney, Diane S; Zheng, Yuxiang; Brash, Alan R
信号转导
发表日期：2014
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Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis

血红素衍生的9-氢过氧亚油酸的环氧醇和三羟基衍生物的空间位阻分析及酶法合成

期刊:Chemistry and Physics of Lipids
影响因子:2.8
doi:10.1016/j.chemphyslip.2013.01.002
Thomas, Christopher P; Boeglin, William E; Garcia-Diaz, Yoel; O'Donnell, Valerie B; Brash, Alan R
发表日期：2013
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Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ.

单核细胞和巨噬细胞会产生新型酮磷脂，在囊性纤维化中可以检测到这些新型酮磷脂，并激活过氧化物酶体增殖物激活受体-γ

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M112.405407
Hammond Victoria J, Morgan Alwena H, Lauder Sarah, Thomas Christopher P, Brown Sarah, Freeman Bruce A, Lloyd Clare M, Davies Jane, Bush Andrew, Levonen Anna-Liisa, Kansanen Emilia, Villacorta Luis, Chen Y Eugene, Porter Ned, Garcia-Diaz Yoel M, Schopfer Francisco J, O'Donnell Valerie B
细胞生物学
巨噬细胞
发表日期：2012
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