日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intralysosomal pathogens differentially influence the proteolytic potential of their niche

溶酶体内病原体对其微环境的蛋白水解潜力产生不同的影响。

Bird, Lauren E; Xu, Bangyan; Thomas, David R; McGowan, Erin N S; Newton, Patrice; Scott, Nichollas E; McConville, Malcolm J; Edgington-Mitchell, Laura E; Newton, Hayley J

Coxiella burnetii manipulates the lysosomal protease cathepsin B to facilitate intracellular success.

伯氏考克斯体操纵溶酶体蛋白酶组织蛋白酶 B 以促进细胞内感染的成功

Bird Lauren E, Xu Bangyan, Hobbs Andrew D, Ziegler Alexander R, Scott Nichollas E, Newton Patrice, Thomas David R, Edgington-Mitchell Laura E, Newton Hayley J

Endocrine-targeting therapies shift the breast microbiome to reduce estrogen receptor-α breast cancer risk

内分泌靶向疗法通过改变乳腺微生物群来降低雌激素受体α乳腺癌风险。

Alana A Arnone ,Yu-Ting Tsai ,J Mark Cline ,Adam S Wilson ,Brian Westwood ,Meghan E Seger ,Akiko Chiba ,Marissa Howard-McNatt ,Edward A Levine ,Alexandra Thomas ,David R Soto-Pantoja ,Katherine L Cook

Coxiella burnetii protein CBU2016 supports CCV expansion

伯氏柯克斯体蛋白CBU2016支持CCV的扩增

Thomas, David R; Garnish, Sarah E; Khoo, Chen Ai; Padmanabhan, Bhavna; Scott, Nichollas E; Newton, Hayley J

Coxiella co-opts the Glutathione Peroxidase 4 to protect the host cell from oxidative stress-induced cell death

科克斯氏体利用谷胱甘肽过氧化物酶4来保护宿主细胞免受氧化应激诱导的细胞死亡。

Loterio, Robson K; Thomas, David R; Andrade, Warrison; Lee, Yi Wei; Santos, Leonardo L; Mascarenhas, Danielle P A; Steiner, Thiago M; Chiaratto, Jéssica; Fielden, Laura F; Lopes, Leticia; Bird, Lauren E; Goldman, Gustavo H; Stojanovski, Diana; Scott, Nichollas E; Zamboni, Dario S; Newton, Hayley J

A high-throughput cytotoxicity screening platform reveals agr-independent mutations in bacteraemia-associated Staphylococcus aureus that promote intracellular persistence.

高通量细胞毒性筛选平台揭示了与菌血症相关的金黄色葡萄球菌中与agr无关的突变,这些突变促进了细胞内持久性

Hachani Abderrahman, Giulieri Stefano G, Guérillot Romain, Walsh Calum J, Herisse Marion, Soe Ye Mon, Baines Sarah L, Thomas David R, Cheung Shane Doris, Hayes Ashleigh S, Cho Ellie, Newton Hayley J, Pidot Sacha, Massey Ruth C, Howden Benjamin P, Stinear Timothy P

Target deconvolution studies of (2R,6R)-hydroxynorketamine: an elusive search

(2R,6R)-羟基去甲氯胺酮的目标反卷积研究:一项难以捉摸的研究

Jordi Bonaventura, Juan L Gomez, Meghan L Carlton, Sherry Lam, Marta Sanchez-Soto, Patrick J Morris, Ruin Moaddel, Hye Jin Kang, Panos Zanos, Todd D Gould, Craig J Thomas, David R Sibley, Carlos A Zarate Jr, Michael Michaelides2

Disruption of Iron Homeostasis and Mitochondrial Metabolism Are Promising Targets to Inhibit Candida auris.

铁稳态和线粒体代谢的破坏是抑制耳念珠菌感染的潜在靶点

Simm Claudia, Weerasinghe Harshini, Thomas David R, Harrison Paul F, Newton Hayley J, Beilharz Traude H, Traven Ana

Perturbation of ATG16L1 function impairs the biogenesis of Salmonella and Coxiella replication vacuoles

ATG16L1功能紊乱会损害沙门氏菌和科克斯氏体复制泡的生物发生。

Lau, Nicole; Thomas, David R; Lee, Yi Wei; Knodler, Leigh A; Newton, Hayley J

Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability

氯胺酮对映体的药理学和行为差异:对滥用责任的影响

Jordi Bonaventura, Sherry Lam, Meghan Carlton, Matthew A Boehm, Juan L Gomez, Oscar Solís, Marta Sánchez-Soto, Patrick J Morris, Ida Fredriksson, Craig J Thomas, David R Sibley, Yavin Shaham, Carlos A Zarate Jr, Michael Michaelides