日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single cell and spatial analysis of immune-hot and immune-cold tumours identifies fibroblast subtypes associated with distinct immunological niches and positive immunotherapy response.

对免疫热肿瘤和免疫冷肿瘤进行单细胞和空间分析,可以识别与不同免疫微环境和积极免疫治疗反应相关的成纤维细胞亚型

Jenkins Benjamin H, Tracy Ian, Rodrigues Maria Fernanda S D, Smith Melanie J L, Martinez Begoña R, Edmond Mark, Mahadevan Sangeetha, Rao Anjali, Zong Hailing, Liu Kai, Aggarwal Abhishek, Li Li, Diehl Lauri, King Emma V, Bates Jamie G, Hanley Christopher J, Thomas Gareth J

Spatial profiling of HPV-stratified head and neck squamous cell carcinoma reveals distinct immune niches and microenvironmental architectures

HPV分层头颈部鳞状细胞癌的空间分析揭示了不同的免疫微环境和微环境结构

Markovits, Ettai; Klymyshyn, Dmytro; Froumine, Roni; Zong, Hailing; Mints, Michael; Mahadevan, Sangeetha; Bloom, Kenneth; Bates, Jamie; Thomas, Gareth J; Diehl, Lauri; Puig, Oscar; Aggarwal, Abhishek

Developing and Validating a Multivariable Prognostic-Predictive Classifier for Treatment Escalation of Oropharyngeal Squamous Cell Carcinoma: The PREDICTR-OPC Study

开发和验证用于口咽鳞状细胞癌治疗升级的多变量预后预测分类器:PREDICTR-OPC 研究

Mehanna, Hisham; Rapozo, Davy; von Zeidler, Sandra V; Harrington, Kevin J; Winter, Stuart C; Hartley, Andrew; Nankivell, Paul; Schache, Andrew G; Sloan, Philip; Odell, Edward W; Thavaraj, Selvam; Hunter, Keith D; Shah, Ketan A; Thomas, Gareth J; Long, Anna; Amel-Kashipaz, Rasoul; Brown, Rachel M; Conn, Brendan; Hall, Gillian L; Matthews, Paul; Weir, Justin; Yeo, Yen; Pring, Miranda; West, Catharine M L; McCaul, James; Golusinski, Pawel; Sitch, Alice; Spruce, Rachel; Batis, Nikolaos; Bryant, Jennifer L; Brooks, Jill M; Jones, Terence M; Buffa, Francesca; Haider, Syed; Robinson, Max

Differentiation signals induce APOBEC3A expression via GRHL3 in squamous epithelia and squamous cell carcinoma

分化信号通过GRHL3诱导鳞状上皮和鳞状细胞癌中APOBEC3A的表达

Smith, Nicola J; Reddin, Ian; Policelli, Paige; Oh, Sunwoo; Zainal, Nur; Howes, Emma; Jenkins, Benjamin; Tracy, Ian; Edmond, Mark; Sharpe, Benjamin; Amendra, Damian; Zheng, Ke; Egawa, Nagayasu; Doorbar, John; Rao, Anjali; Mahadevan, Sangeetha; Carpenter, Michael A; Harris, Reuben S; Ali, Simak; Hanley, Christopher; Buisson, Rémi; King, Emma; Thomas, Gareth J; Fenton, Tim R

A high-throughput 3D X-ray histology facility for biomedical research and preclinical applications

用于生物医学研究和临床前应用的高通量3D X射线组织学平台

Katsamenis, Orestis L; Basford, Philip J; Robinson, Stephanie K; Boardman, Richard P; Konstantinopoulou, Elena; Lackie, Peter M; Page, Anton; Ratnayaka, J Arjuna; Goggin, Patricia M; Thomas, Gareth J; Cox, Simon J; Sinclair, Ian; Schneider, Philipp

Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance

对来自三大洲的宫颈鳞状细胞癌队列进行综合分析,揭示了具有预后意义的保守亚型。

Chakravarthy, Ankur; Reddin, Ian; Henderson, Stephen; Dong, Cindy; Kirkwood, Nerissa; Jeyakumar, Maxmilan; Rodriguez, Daniela Rothschild; Martinez, Natalia Gonzalez; McDermott, Jacqueline; Su, Xiaoping; Egawa, Nagayasau; Fjeldbo, Christina S; Skingen, Vilde Eide; Lyng, Heidi; Halle, Mari Kyllesø; Krakstad, Camilla; Soleiman, Afschin; Sprung, Susanne; Lechner, Matt; Ellis, Peter J I; Wass, Mark; Michaelis, Martin; Fiegl, Heidi; Salvesen, Helga; Thomas, Gareth J; Doorbar, John; Chester, Kerry; Feber, Andrew; Fenton, Tim R

Epithelial to mesenchymal transition influences fibroblast phenotype in colorectal cancer by altering miR-200 levels in extracellular vesicles.

上皮间质转化通过改变细胞外囊泡中 miR-200 的水平影响结直肠癌成纤维细胞的表型

Bhome Rahul, Emaduddin Muhammad, James Victoria, House Louise M, Thirdborough Stephen M, Mellone Massimiliano, Tulkens Joeri, Primrose John N, Thomas Gareth J, De Wever Olivier, Mirnezami Alex H, Sayan A Emre

Characterising cancer-associated fibroblast heterogeneity in non-small cell lung cancer: a systematic review and meta-analysis

非小细胞肺癌中癌症相关成纤维细胞异质性的特征分析:系统评价和荟萃分析

Irvine, Andrew F; Waise, Sara; Green, Edward W; Stuart, Beth; Thomas, Gareth J

Targeting cancer associated fibroblasts to enhance immunotherapy: emerging strategies and future perspectives

靶向癌症相关成纤维细胞以增强免疫疗法:新兴策略和未来展望

Hanley, Christopher J; Thomas, Gareth J

T-cell tumour exclusion and immunotherapy resistance: a role for CAF targeting

T细胞肿瘤排斥和免疫治疗耐药:CAF靶向治疗的作用

Hanley, Christopher J; Thomas, Gareth J