日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Insights derived from testing a library of per- and polyfluoroalkyl substances (PFAS) in a battery of new approach methods (NAMs)

通过对一系列新型检测方法(NAMs)中全氟和多氟烷基物质(PFAS)库进行测试,获得了以下见解

Patlewicz, Grace; Judson, Richard; Paul Friedman, Katie; Wetmore, Barbara A; DeVito, Michael J; Harrill, Joshua A; Carstens, Kelly E; Houck, Keith A; Wambaugh, John F; Padilla, Stephanie; Britton, Katy N; Shafer, Timothy J; Degitz, Sigmund; Nyffeler, Jo; Kreutz, Anna; Richard, Ann M; Williams, Antony J; Coutros, Katherine; Hornung, Michael W; Cowden, John; Everett, Logan J; Willis, Clinton M; Smeltz, Marci G; Clifton, M Scott; Feshuk, Madison; Wall, Jonathan T; Sayre, Risa R; Brown, Jason; Thomas, Russell S

Transcriptomic dose response assessment of PFAS chemicals 3:3 fluorotelomer carboxylic acid, 7:3 fluorotelomer alcohol, and perfluorohexanesulfonamide

PFAS 化学物质 3:3 氟调聚物羧酸、7:3 氟调聚物醇和全氟己烷磺酰胺的转录组剂量反应评估

Mutlu, Esra; Wehmas, Leah; Harrill, Alison H; Devito, Michael; Thomas, Russell S; Hughes, Michael F; Macmillan, Denise; Brennan, Amanda; Bounds, Jackson; Weitekamp, Chelsea A; Everett, Logan J

Subchronic Toxicities of Four Per- and Polyfluoroalkyl Substances (PFASs) by Oral Exposure in Sprague-Dawley Rats

Sprague-Dawley大鼠经口暴露于四种全氟和多氟烷基物质(PFAS)的亚慢性毒性

Kenyon, Elaina M; Devito, Michael J; Patlewicz, Grace; Adams, Linda D; Thomas, Russell S; Ambroso, Jeffrey L; Yang, Xi; Blake, James C; Upadhyay, Bindu G; Furr, Johnathan; Hughes, Michael F

Immunotoxicity of Four Per- and Polyfluoroalkyl Substances Following 28-Day Oral Repeat Dosing in Rats Assessed by the Anti-Sheep Red Blood Cell IgM Response

通过抗绵羊红细胞 IgM 反应评估四种全氟和多氟烷基物质在大鼠中 28 天重复口服给药后的免疫毒性

Hughes, Michael F; DeVito, Michael J; Patlewicz, Grace; Thomas, Russell S; Adams, Linda D; Ambroso, Jeffrey L; Yang, Xi; Upadhyay, Bindu G; Burleson, Stefanie C M; Kenyon, Elaina M

Analytical Quality Evaluation of the Tox21 Compound Library

Tox21化合物库的分析质量评价

Richard, Ann M; Tao, Dingyin; LeClair, Christopher A; Leister, William; Tretyakov, Kirill V; White, Edward 5th; Lewis, Ken C; Sefler, Andrea; Shinn, Paul; Collins, Bradley J; Nguyen, Dac-Trung; Ye, Lin; Zhao, Tongan; Xu, Tuan; Williams, Antony J; Waidyanatha, Suramya; Thomas, Russell S; Tice, Raymond; Simeonov, Anton; Huang, Ruili

Development of the toxicity values database, ToxValDB: A curated resource for experimental and derived human health-relevant toxicity data

毒性值数据库 ToxValDB 的开发:一个汇集实验和衍生的与人类健康相关的毒性数据的精选资源

Wall, Jonathan T; Sayre, Risa R; Smith, Doris; Winter, Samuel; Groover, Maxwell; Hope, Jasmine; Webb, Adriana; Friedman, Katie Paul; Feshuk, Madison; Williams, Antony J; Lowe, Charles; Sipes, Nisha S; Lambert, Jason; Olker, Jennifer H; Thomas, Russell S; Elonen, Colleen; Judson, Richard S; Weitekamp, Chelsea A

High-Throughput Screening to Advance In Vitro Toxicology: Accomplishments, Challenges, and Future Directions

高通量筛选在体外毒理学发展中的应用:成就、挑战与未来方向

Lynch, Caitlin; Sakamuru, Srilatha; Ooka, Masato; Huang, Ruili; Klumpp-Thomas, Carleen; Shinn, Paul; Gerhold, David; Rossoshek, Anna; Michael, Sam; Casey, Warren; Santillo, Michael F; Fitzpatrick, Suzanne; Thomas, Russell S; Simeonov, Anton; Xia, Menghang

60 Years of the 3Rs symposium: Lessons learned and the road ahead

3R原则研讨会60周年:经验教训与未来展望

Balls, Michael; Bass, Rolf; Curren, Rodger; Fentem, Julia; Goldberg, Alan; Hartung, Thomas; Herrmann, Kathrin; Kleinstreuer, Nicole C; Libowitz, Lisa; Parascandola, John; Rowan, Andrew; Spielmann, Horst; Stephens, Martin L; Thomas, Russell S; Tsaioun, Katya

A Comparison of In Vitro Points of Departure with Human Blood Levels for Per- and Polyfluoroalkyl Substances (PFAS)

全氟和多氟烷基物质(PFAS)体外检测点与人体血液浓度的比较

Judson, Richard S; Smith, Doris; DeVito, Michael; Wambaugh, John F; Wetmore, Barbara A; Paul Friedman, Katie; Patlewicz, Grace; Thomas, Russell S; Sayre, Risa R; Olker, Jennifer H; Degitz, Sigmund; Padilla, Stephanie; Harrill, Joshua A; Shafer, Timothy; Carstens, Kelly E

Signature analysis of high-throughput transcriptomics screening data for mechanistic inference and chemical grouping

利用高通量转录组学筛选数据进行特征分析,以进行机制推断和化学分组

Harrill, Joshua A; Everett, Logan J; Haggard, Derik E; Word, Laura J; Bundy, Joseph L; Chambers, Bryant; Harris, Felix; Willis, Clinton; Thomas, Russell S; Shah, Imran; Judson, Richard