日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Microbial signature of pediatric Crohn's disease: Differentiation from functional gastrointestinal disorders and relationship with increased disease activity

儿童克罗恩病的微生物特征:与功能性胃肠疾病的鉴别诊断及其与疾病活动度增加的关系

Levine, Jeremiah; Thomas, Scott C; Xu, Fangxi; Isbiroglu, Adam; Zanganeh, Ryan; Barazani, Lauren; Vardhan, Mridula; Hwang, Samantha; Persaud, Julia Kishanie; Thakor, Nirali; Joseph, Shelly; Trasande, Leonardo; Saxena, Deepak

Systemic Cysteine Elevation Sustains T-Cell Activation to Potentiate PD-1 Blockade

系统性半胱氨酸水平升高可维持T细胞活化,从而增强PD-1阻断作用

Wang, Xiaoshuang; Wang, Zi; Guo, Yuqi; Xu, Fangxi; Zhu, Jinhui; Thomas, Scott C; Saxena, Deepak; Xie, Jinghang; Li, Xin

A Bacteroides fragilis protease activates host PAR(2) to induce intestinal pain and inflammation.

脆弱拟杆菌蛋白酶激活宿主PAR(2),诱发肠道疼痛和炎症。

Lakemeyer Markus, Latorre Rocco, Blazkova Kristyna, Wood Hannah M, Jensen Dane D, Shakil Nayab, Thomas Scott C, Saxena Deepak, Mulpuri Yatendra, Poolman David, Duran Paz, Keller Laura J, Reed David E, Schmidt Brian L, Jiménez-Vargas Néstor N, Xu Fangxi, Lomax Alan E, Bunnett Nigel W, Bogyo Matthew

Succinate modulates oral dysbiosis and inflammation through a succinate receptor 1 dependent mechanism in aged mice.

琥珀酸通过琥珀酸受体 1 依赖性机制调节老年小鼠的口腔菌群失调和炎症

Xu Fangxi, Guo Yuqi, Thomas Scott C, Saxena Anish, Hwang Samantha, Vardhan Mridula, Li Xin

Identification of cannabinoid-sensitive and -resistant oral bacteria

鉴定对大麻素敏感和耐药的口腔细菌

Scott, David A; Lamont, Gwyneth J; Tan, Jinlian; Patel, Arjun P; Guffey, Jack T; Thomas, Scott C; Xu, Fangxi; Diamond, Gill; Saxena, Deepak

Identification of a secreted protease from Bacteroides fragilis that induces intestinal pain and inflammation by cleavage of PAR(2)

从脆弱拟杆菌中鉴定出一种分泌蛋白酶,该蛋白酶通过切割 PAR(2) 诱发肠道疼痛和炎症

Lakemeyer, Markus; Latorre, Rocco; Blazkova, Kristyna; Jensen, Dane; Wood, Hannah M; Shakil, Nayab; Thomas, Scott C; Saxena, Deepak; Mulpuri, Yatendra; Poolman, David; de Haro, Paz Duran; Keller, Laura J; Reed, David E; Schmidt, Brian L; Lomax, Alan E; Bunnett, Nigel W; Bogyo, Matthew

A novel SUCNR1 inhibitor alleviates dysbiosis through inhibition of host responses without direct interaction with host microbiota

一种新型SUCNR1抑制剂可通过抑制宿主反应来缓解菌群失调,而无需与宿主微生物群直接相互作用。

Thomas, Scott C; Guo, Yuqi; Xu, Fangxi; Saxena, Deepak; Li, Xin

Getting off tract: contributions of intraorgan microbiota to cancer in extraintestinal organs

偏离正轨:器官内微生物群对肠外器官癌症的贡献

Thomas, Scott C; Miller, George; Li, Xin; Saxena, Deepak

Electronic Cigarette Use Promotes a Unique Periodontal Microbiome

电子烟的使用会促进独特的牙周微生物群落的形成。

Thomas, Scott C; Xu, Fangxi; Pushalkar, Smruti; Lin, Ziyan; Thakor, Nirali; Vardhan, Mridula; Flaminio, Zia; Khodadadi-Jamayran, Alireza; Vasconcelos, Rebeca; Akapo, Adenike; Queiroz, Erica; Bederoff, Maria; Janal, Malvin N; Guo, Yuqi; Aguallo, Deanna; Gordon, Terry; Corby, Patricia M; Kamer, Angela R; Li, Xin; Saxena, Deepak

Position-Specific Metabolic Probing and Metagenomics of Microbial Communities Reveal Conserved Central Carbon Metabolic Network Activities at High Temperatures

位置特异性代谢探测和微生物群落宏基因组学揭示高温下保守的中心碳代谢网络活性

Thomas, Scott C; Tamadonfar, Kevin O; Seymour, Cale O; Lai, Dengxun; Dodsworth, Jeremy A; Murugapiran, Senthil K; Eloe-Fadrosh, Emiley A; Dijkstra, Paul; Hedlund, Brian P