日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton

蛋白质组学分析揭示了PLK1依赖的G2/M期降解程序以及AKAP2在协调有丝分裂细胞骨架中的作用

Ryan D Mouery ,Kimberly Lukasik ,Carolyn Hsu ,Thomas Bonacci ,Derek L Bolhuis ,Xianxi Wang ,C Allie Mills ,E Drew Toomer ,Owen G Canterbury ,Kevin C Robertson ,Timothy B Branigan ,Nicholas G Brown ,Laura E Herring ,Stephanie L Gupton ,Michael J Emanuele

Mechanisms of USP18 deISGylation revealed by comparative analysis with its human paralog USP41

通过与人类同源物 USP41 的比较分析揭示 USP18 脱ISGylation 的机制

Thomas Bonacci, Derek L Bolhuis, Nicholas G Brown, Michael J Emanuele

USP37 prevents unscheduled replisome unloading through MCM complex deubiquitination

USP37 通过 MCM 复合物去泛素化阻止非计划复制体卸载

Derek L Bolhuis, Dalia Fleifel, Thomas Bonacci, Xianxi Wang, Brandon L Mouery, Jeanette Gowen Cook, Nicholas G Brown, Michael J Emanuele

Proteomic Analysis Reveals a PLK1-Dependent G2/M Degradation Program and Links PKA-AKAP2 to Cell Cycle Control

蛋白质组学分析揭示了 PLK1 依赖的 G2/M 降解程序,并将 PKA-AKAP2 与细胞周期控制联系起来

Ryan D Mouery, Carolyn Hsu, Thomas Bonacci, Derek L Bolhuis, Xianxi Wang, Christine A Mills, E Drew Toomer, Owen G Canterbury, Kevin C Robertson, Timothy B Branigan, Nicholas G Brown, Laura E Herring, Michael J Emanuele

Functional conservation and divergence of the helix-turn-helix motif of E2 ubiquitin-conjugating enzymes

E2泛素结合酶螺旋-转角-螺旋基序的功能保守性和分歧

Kaeli A Welsh #, Derek L Bolhuis #, Anneroos E Nederstigt, Joshua Boyer, Brenda R S Temple, Thomas Bonacci, Li Gu, Alban Ordureau, J Wade Harper, Joshua P Steimel, Qi Zhang, Michael J Emanuele, Joseph S Harrison, Nicholas G Brown

Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming

泛素链延长酶 UBE2S 激活 RING E3 连接酶 APC/C 进行底物引发

Raquel C Martinez-Chacin, Tatyana Bodrug, Derek L Bolhuis, Katarzyna M Kedziora, Thomas Bonacci, Alban Ordureau, Morgan E Gibbs, Florian Weissmann, Renping Qiao, Gavin D Grant, Jeanette G Cook, Jan-Michael Peters, J Wade Harper, Michael J Emanuele, Nicholas G Brown

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators

通过计算机模拟 APC/C 底物的发现,揭示了 UHRF1 和其他染色质调节剂的细胞周期依赖性降解

Jennifer L Franks, Raquel C Martinez-Chacin, Xianxi Wang, Rochelle L Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L Bolhuis, Taylor P Enrico, Ryan D Mouery, Jeffrey S Damrauer, Feng Yan, Joseph S Harrison, M Ben Major, Katherine A Hoadley, Aussie Suzuki, Scott B Rothbart, Nicholas G Brown, M

FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer

USP21介导的FOXM1去泛素化调控基底样乳腺癌细胞的细胞周期进程和紫杉醇敏感性

Anthony Arceci ,Thomas Bonacci ,Xianxi Wang ,Kyle Stewart ,Jeffrey S Damrauer ,Katherine A Hoadley ,Michael J Emanuele

Cezanne/OTUD7B is a cell cycle-regulated deubiquitinase that antagonizes the degradation of APC/C substrates

Cezanne/OTUD7B 是一种细胞周期调节的去泛素化酶,可拮抗 APC/C 底物的降解

Thomas Bonacci, Aussie Suzuki, Gavin D Grant, Natalie Stanley, Jeanette G Cook, Nicholas G Brown, Michael J Emanuele

Regulation of NUB1 Activity through Non-Proteolytic Mdm2-Mediated Ubiquitination

通过非蛋白水解 Mdm2 介导的泛素化调节 NUB1 活性

Thomas Bonacci, Stéphane Audebert, Luc Camoin, Emilie Baudelet, Juan-Lucio Iovanna, Philippe Soubeyran