日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

VISTA checkpoint inhibition by pH-selective antibody SNS-101 with optimized safety and pharmacokinetic profiles enhances PD-1 response

VISTA 采用 pH 选择性抗体 SNS-101 进行检查点抑制,该抗体具有优化的安全性和药代动力学特征,可增强 PD-1 反应。

Thomas Thisted ,F Donelson Smith ,Arnab Mukherjee ,Yuliya Kleschenko ,Feng Feng ,Zhi-Gang Jiang ,Timothy Eitas ,Kanam Malhotra ,Zuzana Biesova ,Adejumoke Onumajuru ,Faith Finley ,Anokhi Cifuentes ,Guolin Zhang ,Gaëlle H Martin ,Yoshiko Takeuchi ,Kader Thiam ,Robert D Schreiber ,Edward H van der Horst

Myeloid and dendritic cells enhance therapeutics-induced cytokine release syndrome features in humanized BRGSF-HIS preclinical model

髓系细胞和树突状细胞在人源化 BRGSF-HIS 临床前模型中增强治疗诱导的细胞因子释放综合征特征

Gaëlle H Martin, Alexis Gonon, Perrine Martin-Jeantet, Florence Renart-Depontieu, Zuzana Biesova, Anokhi Cifuentes, Arnab Mukherjee, Thomas Thisted, Astrid Doerner, Dean O Campbell, Ludovic Bourré, Edward H van der Horst, Amélie Rezza, Kader Thiam

Attenuating nicotine's effects with high affinity human anti-nicotine monoclonal antibodies

利用高亲和力人类抗尼古丁单克隆抗体减弱尼古丁的影响

Michael D Raleigh, Nicola Beltraminelli, Stephanie Fallot, Mark G LeSage, Amy Saykao, Paul R Pentel, Steve Fuller, Thomas Thisted, Zuzanna Biesova, Stephen Horrigan, Darryl Sampey, Bin Zhou, Matthew W Kalnik

Optimization of a nicotine degrading enzyme for potential use in treatment of nicotine addiction

优化尼古丁降解酶以用于治疗尼古丁成瘾

Thomas Thisted, Zuzana Biesova, Celine Walmacq, Everett Stone, Max Rodnick-Smith, Shaheda S Ahmed, Stephen K Horrigan, Bo Van Engelen, Charles Reed, Matthew W Kalnik