日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Rhesus macaques with an OPA1 mutation demonstrate features of autosomal dominant optic atrophy

携带 OPA1 基因突变的恒河猴表现出常染色体显性遗传性视神经萎缩的特征。

Jaggers, Tracy N; Ripolles-Garcia, Ana; Moshiri, Ala; Story, Brett D; Wang, Jun; Chen, Rui; Moore, Lucy G; Teixeira, Leandro B C; Shim, Jaeho; Raposo, Ana C; Casanova, Maria Isabel; Le, Sophie M; Park, Sangwan; Young, Laura J; Kim, Soohyun; Roszak, Karolina P; Ureno, Vanessa; Karpinen, Paige M; Echeverria, Nayeli; Ardon, Monica; Leonard, Brian C; Knipe, Marguerite; Bliss-Moreau, Eliza; Fortune, Brad; Stout, J Timothy; Rogers, Jeffrey; Marsh-Armstrong, Nicholas; Thomasy, Sara M

TAZ (Wwtr1) deficiency leads to ER stress and mitochondrial dysfunction in a mouse model of Fuchs' endothelial corneal dystrophy

TAZ (Wwtr1) 缺乏会导致 Fuchs 内皮角膜营养不良小鼠模型出现内质网应激和线粒体功能障碍。

Park, Sangwan; Ramarapu, Raneesh; Lim, Jaegook; Khan, Sabina; Khan, Meher J; Stoehr, William R; Leonard, Brian C; Thomasy, Sara M

A molecular and spatial resource defining tubulin isotype organization during corneal development

定义角膜发育过程中微管蛋白同工型组织的分子和空间资源

Ramarapu, R; Stoehr, W R; Miesen, M; Border, S; Thomasy, S M; Rogers, C D

Safety and efficacy of CRISPR-mediated genome ablation of VEGFA as a treatment for choroidal neovascularization in nonhuman primate eyes.

CRISPR介导的VEGFA基因组消融治疗非人灵长类动物眼脉络膜新生血管的安全性和有效性。

Sin Tzu-Ni, Tng Nicole, Dragoli Jack, Ramesh Kumar Sruthi, Villafuerte-Trisolini Carol, Chung Sook Hyun, Tu Lien, Le Sophie M, Shim Jae Ho, Pepple Kathryn L, Ravindran Resmi, Khan Imran H, Moshiri Ala, Thomasy Sara M, Yiu Glenn

Safety and biocompatibility of a novel biodegradable aflibercept-drug delivery system in rhesus macaques

新型可生物降解阿柏西普药物递送系统在恒河猴中的安全性和生物相容性

Story, Brett D; Park, Sangwan; Roszak, Karolina; Shim, Jaeho; Motta, Monica; Ferneding, Michelle; Rudeen, Kayla M; Blandino, Andrew; Ardon, Monica; Le, Sophie; Teixeira, Leandro B C; Yiu, Glenn; Mieler, William F; Thomasy, Sara M; Kang-Mieler, Jennifer J

Systemic and Local Lipids in Nonhuman Primates With Drusen and Age-Related Maculopathies

非人灵长类动物视网膜玻璃膜疣和年龄相关性黄斑病变中的系统性和局部脂质

Villafuerte-Trisolini, Carol; Le, Sophie M; Sin, Tzu-Ni; Huynh, Leon; Gong, Megan; Shen, Tony; Heo, Jaewon; Roszak, Karolina; Raposo, Ana Santos; Graham, James; Havel, Peter; Choy, Kevin; Farsiu, Sina; Thomasy, Sara M; Yiu, Glenn

Clic6 Deficiency Triggers Aberrant Apical Microvilli in RPE.

Clic6 缺陷引发 RPE 中异常的顶端微绒毛

Park Sangwan, Suvarnpradip Naran, Kasiri Niusha, Yiu Glenn, Thomasy Sara M, Imai Denise M, Lloyd K C Kent, Leonard Brian C, Moshiri Ala

Spontaneous refractive error, ocular biometry and age related lens changes in a population of geriatric rhesus macaques

老年恒河猴群体中的自发性屈光不正、眼部生物测量和与年龄相关的晶状体变化

Ross, Jonathon M; Roszak, Karolina; Ripolles-Garcia, Ana; Yiu, Glenn; Murphy, Christopher J; Moshiri, Ala; Miyagi, Hidetaka; Strøm, Ann R; Kim, Soohyun; Park, Sangwan; Casanova, M Isabel; Morse, Lawrence S; Marangakis, Ariana; Chang, Connor; Garzel, Laura M; Roberts, Jeffrey A; Thomasy, Sara M

The role of epithelial membrane-associated mucin 4 in ocular surface health and corneal wound healing

上皮膜相关黏蛋白4在眼表健康和角膜伤口愈合中的作用

Adelman, Sara A; Hisey, Erin A; Park, Sangwan; Lantyer-Araujo, Nayone; Quan, Melinda M; Sandberg, Kathryn; Khan, Sabina; Khan, Meher; Dreyer, Courtney A; Thomasy, Sara M; Carraway, Kermit L 3rd; Morgan, Joshua T; Leonard, Brian C

Genetic diversity of 1,845 rhesus macaques improves genetic variation interpretation and identifies disease models

对1845只恒河猴的遗传多样性分析有助于更好地解读遗传变异并识别疾病模型

Wang, Jun; Wang, Meng; Moshiri, Ala; Harris, R Alan; Raveendran, Muthuswamy; Nguyen, Tracy; Kim, Soohyun; Young, Laura; Wang, Keqing; Wiseman, Roger; O'Connor, David H; Johnson, Zach; Martinez, Melween; Montague, Michael J; Sayers, Ken; Lyke, Martha; Vallender, Eric; Stout, Tim; Li, Yumei; Thomasy, Sara M; Rogers, Jeffrey; Chen, Rui