日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Recombinant factor IX-Fc fusion protein (rFIXFc) demonstrates safety and prolonged activity in a phase 1/2a study in hemophilia B patients

重组凝血因子IX-Fc融合蛋白(rFIXFc)在B型血友病患者的1/2a期研究中显示出安全性和持久活性。

Shapiro, Amy D; Ragni, Margaret V; Valentino, Leonard A; Key, Nigel S; Josephson, Neil C; Powell, Jerry S; Cheng, Gregory; Thompson, Arthur R; Goyal, Jaya; Tubridy, Karen L; Peters, Robert T; Dumont, Jennifer A; Euwart, Donald; Li, Lian; Hallén, Bengt; Gozzi, Peter; Bitonti, Alan J; Jiang, Haiyan; Luk, Alvin; Pierce, Glenn F

Inhibitors of factor VIII in black patients with hemophilia

黑人血友病患者体内因子VIII抑制剂

Viel, Kevin R; Ameri, Afshin; Abshire, Thomas C; Iyer, Rathi V; Watts, Raymond G; Lutcher, Charles; Channell, Cynthia; Cole, Shelley A; Fernstrom, Karl M; Nakaya, Shelley; Kasper, Carol K; Thompson, Arthur R; Almasy, Laura; Howard, Tom E

Lineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti-factor VIII immune responses

在抗VIII因子免疫应答的不同阶段分离出的人类T细胞克隆谱系,包括辅助性T细胞17/辅助性T细胞1细胞。

Ettinger, Ruth A; James, Eddie A; Kwok, William W; Thompson, Arthur R; Pratt, Kathleen P

CD4+FOXP3+ regulatory T cells confer long-term regulation of factor VIII-specific immune responses in plasmid-mediated gene therapy-treated hemophilia mice

CD4+FOXP3+调节性T细胞在质粒介导的基因治疗治疗的血友病小鼠中赋予因子VIII特异性免疫反应的长期调节作用。

Miao, Carol H; Harmeling, Benjamin R; Ziegler, Steven F; Yen, Benjamin C; Torgerson, Troy; Chen, Liping; Yau, Roger J; Peng, Baowei; Thompson, Arthur R; Ochs, Hans D; Rawlings, David J

The factor VIII C1 domain contributes to platelet binding.

VIII因子C1结构域有助于血小板结合

Hsu Ting-Chang, Pratt Kathleen P, Thompson Arthur R

Immunomodulation of transgene responses following naked DNA transfer of human factor VIII into hemophilia A mice

将人凝血因子VIII裸DNA转移到A型血友病小鼠体内后,转基因反应的免疫调节

Miao, Carol H; Ye, Peiqing; Thompson, Arthur R; Rawlings, David J; Ochs, Hans D