日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Integration of functional genomics and statistical fine-mapping systematically characterizes adult-onset and childhood-onset asthma genetic associations

功能基因组学与统计精细定位的整合系统地表征了成人发病型和儿童发病型哮喘的遗传关联。

Zhong, Xiaoyuan; Mitchell, Robert; Billstrand, Christine; Thompson, Emma E; Sakabe, Noboru J; Aneas, Ivy; Salamone, Isabella M; Gu, Jing; Sperling, Anne I; Schoettler, Nathan; Nóbrega, Marcelo A; He, Xin; Ober, Carole

Genetic contributions to epigenetic-defined endotypes of allergic phenotypes in children

遗传因素对儿童过敏表型表观遗传定义的内型的影响

Thompson, Emma E; Zhong, Xiaoyuan; Carbonetto, Peter; Morin, Andréanne; Willwerscheid, Jason; Visness, Cynthia M; Bacharier, Leonard B; Kattan, Meyer; O'Connor, George T; Rivera-Spoljaric, Katherine; Wood, Robert A; Gold, Diane R; Khurana Hershey, Gurjit K; Johnson, Christine C; Miller, Rachel L; Seroogy, Christine M; Zoratti, Edward M; Gergen, Peter J; Levin, Albert M; Altman, Matthew C; Hartert, Tina; Stephens, Matthew; Jackson, Daniel J; Gern, James E; McKennan, Christopher G; Ober, Carole

Association of 17q12-q21 Asthma Risk Locus with Clinical Severity of Infant Respiratory Syncytial Virus Infection

17q12-q21哮喘风险位点与婴儿呼吸道合胞病毒感染临床严重程度的关联

Turi, Kedir N; McKennan, Christopher; Rosas-Salazar, Christian; Gebretsedik, Tebeb; Newcomb, Dawn C; Thompson, Emma E; Gern, James; Chappell, James; Anderson, Larry; Ober, Carole; Hartert, Tina

Vitamin C supplementation to pregnant smokers alters asthma- and allergy-associated CpGs in child buccal DNA at 5 years of age

孕期吸烟者补充维生素C会改变5岁儿童口腔DNA中与哮喘和过敏相关的CpG位点。

Shorey-Kendrick, Lyndsey E; McEvoy, Cindy T; Milner, Kristin; Harris, Julia; Brownsberger, Julie; Tepper, Robert S; Park, Byung; Gao, Lina; Vu, Annette; Morris, Cynthia D; Thompson, Emma E; Ober, Carole; Spindel, Eliot R

Prenatal ambient air pollution associations with DNA methylation in asthma- and allergy-relevant genes: findings from ECHO

产前环境空气污染与哮喘和过敏相关基因的DNA甲基化之间的关联:来自ECHO的研究结果

Palmore, Meredith; Thompson, Emma E; Fang, Fang; Bastain, Theresa M; Breton, Carrie; Collingwood, Scott; Gilliland, Frank D; Gold, Diane R; Habre, Rima; Hartert, Tina; Khurana Hershey, Gurjit K; Jackson, Daniel J; Miller, Rachel; Ryan, Patrick; Shorey-Kendrick, Lyndsey; Spindel, Eliot R; Stanford, Joseph; Gern, James; McKennan, Chris; Ober, Carole; Ladd-Acosta, Christine

Immune pathways and perinatal environmental exposures contribute to epigenetic gestational age prediction and acceleration

免疫通路和围产期环境暴露会影响表观遗传学对妊娠年龄的预测和加速。

Eapen, Amy A; Loveless, Ian M; Pan, Mingming; Liang, Xiaoyu; Urquhart, Audrey; Straughen, Jennifer; Cassidy-Bushrow, Andrea E; Sitarik, Alexandra R; Simmerman, Neil; Thompson, Emma E; Kottyan, Leah; Ober, Carole; Johnson, Christine C; Zoratti, Edward; Levin, Albert M

Cumulative Genetic Risk for Asthma Contributes to Disease Severity in Children with Asthma living in Urban Environments

城市环境中儿童哮喘的累积遗传风险会加重病情。

Dapas, Matthew; Wentworth-Sheilds, William; Thompson, Emma E; Kumar, Rajesh; Lippner, Elizabeth; Wood, Robert A; O'Connor, George T; Khurana Hershey, Gurjit K; Gruchalla, Rebecca S; Liu, Andrew H; Zoratti, Edward M; Bacharier, Leonard B; Lovinsky-Desir, Stephanie; Gill, Michele A; Sheehan, William J; Patel, Shilpa J; Altman, Matthew C; Gern, James E; Visness, Cynthia M; Gergen, Peter J; Becker, Patrice M; Jackson, Daniel J; Ober, Carole

Shared loci but distinct variants underlie genetic architecture of allergic diseases.

过敏性疾病的遗传结构由共同的基因位点和不同的变异构成

Salamone Isabella M, Zhong Xiaoyuan, Sakabe Noboru J, Mitchell Robert, Wentworth-Sheilds William, Zhang Li, Thompson Emma E, Decker Donna C, Rische Clayton H, Liu Xuanyao, Schoettler Nathan, Ober Carole, He Xin, Nóbrega Marcelo A

Multi-omics in nasal epithelium reveals three axes of dysregulation for asthma risk in the African Diaspora populations

鼻上皮多组学研究揭示了非洲裔人群哮喘风险的三个失调轴

Szczesny, Brooke; Boorgula, Meher Preethi; Chavan, Sameer; Campbell, Monica; Johnson, Randi K; Kammers, Kai; Thompson, Emma E; Cox, Madison S; Shankar, Gautam; Cox, Corey; Morin, Andréanne; Lorizio, Wendy; Daya, Michelle; Kelada, Samir N P; Beaty, Terri H; Doumatey, Ayo P; Cruz, Alvaro A; Watson, Harold; Naureckas, Edward T; Giles, B Louise; Arinola, Ganiyu A; Sogaolu, Olumide; Falade, Adegoke G; Hansel, Nadia N; Yang, Ivana V; Olopade, Christopher O; Rotimi, Charles N; Landis, R Clive; Figueiredo, Camila A; Altman, Matthew C; Kenny, Eimear; Ruczinski, Ingo; Liu, Andrew H; Ober, Carole; Taub, Margaret A; Barnes, Kathleen C; Mathias, Rasika A

A functional genomics pipeline to identify high-value asthma and allergy CpGs in the human methylome

功能基因组学流程用于识别人类甲基化组中高价值的哮喘和过敏性CpG位点

Morin, Andréanne; Thompson, Emma E; Helling, Britney A; Shorey-Kendrick, Lyndsey E; Faber, Pieter; Gebretsadik, Tebeb; Bacharier, Leonard B; Kattan, Meyer; O'Connor, George T; Rivera-Spoljaric, Katherine; Wood, Robert A; Barnes, Kathleen C; Mathias, Rasika A; Altman, Matthew C; Hansen, Kasper; McEvoy, Cindy T; Spindel, Eliot R; Hartert, Tina; Jackson, Daniel J; Gern, James E; McKennan, Chris G; Ober, Carole