日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Chromosome engineering to correct a complex rearrangement on Chromosome 8 reveals the effects of 8p syndrome on gene expression and neural differentiation

通过染色体工程纠正8号染色体上的复杂重排,揭示了8p综合征对基因表达和神经分化的影响

Lee, Sophia N; Banda, Erin C; Qiao, Lu; Thompson, Sarah L; Singh, Karan; Hagenson, Ryan A; Davoli, Teresa; Pinter, Stefan F; Sheltzer, Jason M

A clinical-stage oncology compound selectively targets drug-resistant cancers

一种处于临床阶段的肿瘤化合物可选择性地靶向耐药性癌症。

Long, Kaitlin; Bhattacharjee, Debanjan; Newman-Stonebraker, Samuel H; Suhr, Simon; Mercado, Brandon Q; Scheib, Emily; Tighe, Anthony; Romero, Luciano; Thompson, Sarah L; Sausville, Erin L; John, Kristen M; Julian, Linda; Mishra, Sanat; Klingbeil, Olaf; Gupta, Punya; Bhatt, Uditi; Gao, Allen C; Ricardo, Sara; Vakoc, Christopher R; Bornhauser, Beat C; Corsello, Steven M; Taylor, Stephen S; Chen, Jue; Holland, Patrick L; Sheltzer, Jason M

Chromosome engineering to correct a complex rearrangement on Chromosome 8 reveals the effects of 8p syndrome on gene expression and neural differentiation

通过染色体工程纠正8号染色体上的复杂重排,揭示了8p综合征对基因表达和神经分化的影响

Lee, Sophia N; Banda, Erin C; Qiao, Lu; Thompson, Sarah L; Singh, Karan; Hagenson, Ryan A; Davoli, Teresa; Pinter, Stefan F; Sheltzer, Jason M

On-target toxicity limits the efficacy of CDK11 inhibition against cancers with 1p36 deletions.

靶向毒性限制了 CDK11 抑制剂对 1p36 缺失癌症的疗效

Julian Linda, Crozier Lisa, Lukow Devon, Mishra Sanat, Swamy Aditi, Hagenson Ryan A, Sennhenn Peter, Sausville Erin L, Mendelson Brianna, Chuaqui Claudio, Qiao Lu, Vasudevan Anand, Lin Kuan-Ting, Bhatia Sonam, Bertomeu Thierry, Chatr-Aryamontri Andrew, Zhang Li, Rees Matthew G, Ronan Melissa M, Roth Jennifer A, Nottoli Timothy, Bai Suxia, Lakshmipathi Jayalakshmi, Muthusamy Viswanathan, Van Vranken Jonathan G, Gygi Steven P, Thompson Sarah L, Smith Joan C, Anderson Kendall, Shah Sanjana, Bindra Ranjit S, Akerman Martin, Spector David L, Krainer Adrian R, Sheltzer Jason M

Aneuploidy in human cancer: new tools and perspectives

人类癌症中的非整倍体:新的工具和视角

Lakhani, Asad A; Thompson, Sarah L; Sheltzer, Jason M

Chromosomes and cancer cells

染色体与癌细胞

Thompson, Sarah L; Compton, Duane A

Yet1p-Yet3p interacts with Scs2p-Opi1p to regulate ER localization of the Opi1p repressor

Yet1p-Yet3p 与 Scs2p-Opi1p 相互作用,调控 Opi1p 抑制因子在内质网的定位。

Wilson, Joshua D; Thompson, Sarah L; Barlowe, Charles

Specific treatment of problems of the spine (STOPS): design of a randomised controlled trial comparing specific physiotherapy versus advice for people with subacute low back disorders

脊柱问题专项治疗(STOPS):一项随机对照试验的设计,旨在比较针对亚急性腰背部疾病患者的专项物理疗法与常规建议。

Hahne, Andrew J; Ford, Jon J; Surkitt, Luke D; Richards, Matthew C; Chan, Alexander Y P; Thompson, Sarah L; Hinman, Rana S; Taylor, Nicholas F

Targeting the cyclin E-Cdk-2 complex represses lung cancer growth by triggering anaphase catastrophe

靶向细胞周期蛋白E-Cdk-2复合物可通过触发后期灾难抑制肺癌生长

Galimberti, Fabrizio; Thompson, Sarah L; Liu, Xi; Li, Hua; Memoli, Vincent; Green, Simon R; DiRenzo, James; Greninger, Patricia; Sharma, Sreenath V; Settleman, Jeff; Compton, Duane A; Dmitrovsky, Ethan

Mechanisms of chromosomal instability

染色体不稳定的机制

Thompson, Sarah L; Bakhoum, Samuel F; Compton, Duane A