日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Acute Cold Exposure Cell-Autonomously Reduces mTORC1 Signaling and Protein Synthesis Independent of AMPK

急性寒冷暴露通过细胞自主的方式降低 mTORC1 信号传导和蛋白质合成,且该过程不依赖于 AMPK。

Sung, Benjamin Y; Ford, Eliza J; Foster, Daniel J; Fullmer, Kyler J; Cromwell, Cosette; Viollet, Benoit; Thomson, David M

Chronic treatment of old mice with AICAR reverses age-related changes in exercise performance and skeletal muscle gene expression.

用 AICAR 对老年小鼠进行长期治疗可逆转与年龄相关的运动能力和骨骼肌基因表达的变化

Wilcox Shalene H, Calixto Jouber, Dray Steven D, Rasch Daniel M, Smith Andrew H, Brodowski Kole D, Hill Jonathon T, Thomson David M

Stem cell-derived synthetic embryos self-assemble by exploiting cadherin codes and cortical tension

干细胞衍生的合成胚胎利用钙粘蛋白代码和皮质张力进行自组装

Min Bao, Jake Cornwall-Scoones, Estefania Sanchez-Vasquez, Andy L Cox, Dong-Yuan Chen, Joachim De Jonghe, Shahriar Shadkhoo, Florian Hollfelder, Matt Thomson, David M Glover, Magdalena Zernicka-Goetz

Mice lacking melatonin MT2 receptors exhibit attentional deficits, anxiety and enhanced social interaction

缺乏褪黑素MT2受体的小鼠表现出注意力缺陷、焦虑和社交互动增强。

Thomson, David M; Mitchell, Emma J; Openshaw, Rebecca L; Pratt, Judith A; Morris, Brian J

Map2k7 Haploinsufficiency Induces Brain Imaging Endophenotypes and Behavioral Phenotypes Relevant to Schizophrenia

Map2k7单倍体不足诱发与精神分裂症相关的脑成像内表型和行为表型

Openshaw, Rebecca L; Thomson, David M; Thompson, Rhiannon; Penninger, Josef M; Pratt, Judith A; Morris, Brian J; Dawson, Neil

Drug-responsive autism phenotypes in the 16p11.2 deletion mouse model: a central role for gene-environment interactions

16p11.2缺失小鼠模型中药物反应性自闭症表型:基因-环境相互作用的核心作用

Mitchell, Emma J; Thomson, David M; Openshaw, Rebecca L; Bristow, Greg C; Dawson, Neil; Pratt, Judith A; Morris, Brian J

A Novel Approach to Single Cell RNA-Sequence Analysis Facilitates In Silico Gene Reporting of Human Pluripotent Stem Cell-Derived Retinal Cell Types

单细胞 RNA 序列分析的新方法有助于通过计算机报告人类多能干细胞衍生的视网膜细胞类型基因

M Joseph Phillips, Peng Jiang, Sara Howden, Patrick Barney, Jee Min, Nathaniel W York, Li-Fang Chu, Elizabeth E Capowski, Abigail Cash, Shivani Jain, Katherine Barlow, Tasnia Tabassum, Ron Stewart, Bikash R Pattnaik, James A Thomson, David M Gamm

Regulation of WNT Signaling by VSX2 During Optic Vesicle Patterning in Human Induced Pluripotent Stem Cells

VSX2 在人类诱导性多能干细胞视泡形成过程中对 WNT 信号的调控

Elizabeth E Capowski, Lynda S Wright, Kun Liang, M Joseph Phillips, Kyle Wallace, Anna Petelinsek, Anna Hagstrom, Isabel Pinilla, Katarzyna Borys, Jessica Lien, Jee Hong Min, Sunduz Keles, James A Thomson, David M Gamm

Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation

人类胚胎干细胞分化过程中 MITF 表达的缺失会破坏视网膜色素上皮的发育和视泡细胞的增殖

Elizabeth E Capowski, Joseph M Simonett, Eric M Clark, Lynda S Wright, Sara E Howden, Kyle A Wallace, Anna M Petelinsek, Isabel Pinilla, M Joseph Phillips, Jason S Meyer, Bernard L Schneider, James A Thomson, David M Gamm

Ectopic lipid deposition and the metabolic profile of skeletal muscle in ovariectomized mice.

卵巢切除小鼠骨骼肌异位脂质沉积及代谢特征

Jackson Kathryn C, Wohlers Lindsay M, Lovering Richard M, Schuh Rosemary A, Maher Amy C, Bonen Arend, Koves Timothy R, Ilkayeva Olga, Thomson David M, Muoio Deborah M, Spangenburg Espen E