2-Aminomethylene-5-sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth.
2-氨基亚甲基-5-磺酰噻唑类赖氨酰氧化酶(LOX)和LOXL2抑制剂在延缓肿瘤生长方面显示出显著疗效
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.9b01112
Smithen Deborah A, Leung Leo M H, Challinor Mairi, Lawrence Rae, Tang HaoRan, Niculescu-Duvaz Dan, Pearce Simon P, Mcleary Robert, Lopes Filipa, Aljarah Mohammed, Brown Michael, Johnson Louise, Thomson Graeme, Marais Richard, Springer Caroline