日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Low-dose interleukin-2 in patients with mild to moderate Alzheimer's disease: a randomized clinical trial

低剂量白细胞介素-2治疗轻度至中度阿尔茨海默病患者:一项随机临床试验

Faridar, Alireza; Gamez, Nazaret; Li, Daling; Wang, Yanling; Boradia, Reena; Thome, Aaron D; Zhao, Weihua; Beers, David R; Thonhoff, Jason R; Nakawah, Mohammad O; Román, Gustavo C; Volpi, John J; Toledo, Jon B; George, Michael; Davis, Charles S; Pascual, Belen; Grundman, Michael; Masdeu, Joseph C; Appel, Stanley H

Peripheral monocyte transcriptional signatures of inflammation and oxidative stress in Parkinson's disease

帕金森病中外周单核细胞炎症和氧化应激的转录特征

Thome, Aaron D; Wang, Jinghong; Atassi, Farah; Thonhoff, Jason R; Faridar, Alireza; Zhao, Weihua; Beers, David R; Lai, Eugene C; Appel, Stanley H

Nutrition regulates reproductive senescence and terminal investment across the reproductive cycle of a long-lived mammal

营养在长寿哺乳动物的整个生殖周期中调节生殖衰老和终末投入。

LaSharr, Tayler N; Dwinnell, Samantha P H; Jakopak, Rhiannon P; Rafferty, Rebekah T; Randall, Jill; Stewart, Cheyenne; Kaiser, Rusty; Thonhoff, Mark; Scurlock, Brandon; Fieseler, Troy; Fralick, Gary; Monteith, Kevin L

A phase 1 proof-of-concept study evaluating safety, tolerability, and biological marker responses with combination therapy of CTLA4-Ig and interleukin-2 in amyotrophic lateral sclerosis

一项 1 期概念验证研究,评估 CTLA4-Ig 和白细胞介素-2 联合治疗肌萎缩侧索硬化症的安全性、耐受性和生物标志物反应

Jason R Thonhoff, David R Beers, Weihua Zhao, Alireza Faridar, Aaron Thome, Shixiang Wen, Aijun Zhang, Jinghong Wang, Stanley H Appel

Combined Regulatory T-Lymphocyte and IL-2 Treatment Is Safe, Tolerable, and Biologically Active for 1 Year in Persons With Amyotrophic Lateral Sclerosis

对于肌萎缩侧索硬化症患者,联合调节性 T 淋巴细胞和 IL-2 治疗一年后仍安全、可耐受且具有生物活性

Jason R Thonhoff, James D Berry, Eric A Macklin, David R Beers, Patricia A Mendoza, Weihua Zhao, Aaron D Thome, Fabio Triolo, James J Moon, Sabrina Paganoni, Merit Cudkowicz, Stanley H Appel

Tregs Attenuate Peripheral Oxidative Stress and Acute Phase Proteins in ALS.

Tregs可减轻ALS患者的外周氧化应激和急性期蛋白

Beers David R, Thonhoff Jason R, Faridar Alireza, Thome Aaron D, Zhao Weihua, Wen Shixiang, Appel Stanley H

Ex vivo expanded human regulatory T cells modify neuroinflammation in a preclinical model of Alzheimer's disease

体外扩增的人类调节性 T 细胞可改变阿尔茨海默病临床前模型中的神经炎症

Alireza Faridar, Matthew Vasquez, Aaron D Thome, Zheng Yin, Hui Xuan, Jing Hong Wang, Shixiang Wen, Xuping Li, Jason R Thonhoff, Weihua Zhao, Hong Zhao, David R Beers, Stephen T C Wong, Joseph C Masdeu, Stanley H Appel

Extracellular Vesicles Derived From Ex Vivo Expanded Regulatory T Cells Modulate In Vitro and In Vivo Inflammation

来自体外扩增的调节性 T 细胞的细胞外囊泡调节体内和体外的炎症

Aaron D Thome, Jason R Thonhoff, Weihua Zhao, Alireza Faridar, Jinghong Wang, David R Beers, Stanley H Appel

Biomarkers of Animal Nutrition: From Seasonal to Lifetime Indicators of Environmental Conditions

动物营养生物标志物:从季节性到终生环境条件指标

Smiley, Rachel A; LaSharr, Tayler N; Abernathy, Heather N; Shakeri, Yasaman N; Levine, Rebecca L; Rankins, Seth T; Jakopak, Rhiannon P; Rafferty, Rebekah T; Kolek, Jaron T; Wagler, Brittany L; Dwinnell, Samantha P H; Robinson, Timothy J; Randall, Jill E; Kaiser, Rusty C; Thonhoff, Mark; Scurlock, Brandon; Fieseler, Troy; Fralick, Gary L; Monteith, Kevin L

Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson's disease

功能失调的调节性 T 淋巴细胞的体外扩增可恢复帕金森病的抑制功能

Aaron D Thome, Farah Atassi, Jinghong Wang, Alireza Faridar, Weihua Zhao, Jason R Thonhoff, David R Beers, Eugene C Lai, Stanley H Appel