日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

β-Cell Obligation in α-Cell Glucagon Response to Low Glucose

β细胞在α细胞对低血糖的胰高血糖素反应中的作用

Herrera, Pedro; Bru-Tari, Eva; Perez-Frances, Marta; Thorel, Fabrizio

Author Correction: Generation of human islet cell type-specific identity genesets

作者更正:人类胰岛细胞类型特异性身份基因集的生成

van Gurp, Léon; Fodoulian, Leon; Oropeza, Daniel; Furuyama, Kenichiro; Bru-Tari, Eva; Vu, Anh Nguyet; Kaddis, John S; Rodríguez, Iván; Thorel, Fabrizio; Herrera, Pedro L

Author Correction: Pancreatic Ppy-expressing γ-cells display mixed phenotypic traits and the adaptive plasticity to engage insulin production

作者更正:胰腺中表达Ppy的γ细胞表现出混合表型特征,并具有适应性可塑性以启动胰岛素生成。

Perez-Frances, Marta; van Gurp, Léon; Abate, Maria Valentina; Cigliola, Valentina; Furuyama, Kenichiro; Bru-Tari, Eva; Oropeza, Daniel; Carreaux, Taïna; Fujitani, Yoshio; Thorel, Fabrizio; Herrera, Pedro L

Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx

通过靶向Dnmt1和Arx将成年胰岛α细胞转化为β细胞

Chakravarthy, Harini; Gu, Xueying; Enge, Martin; Dai, Xiaoqing; Wang, Yong; Damond, Nicolas; Downie, Carolina; Liu, Kathy; Wang, Jing; Xing, Yuan; Chera, Simona; Thorel, Fabrizio; Quake, Stephen; Oberholzer, Jose; MacDonald, Patrick E; Herrera, Pedro L; Kim, Seung K

Dnmt1 activity is dispensable in δ-cells but is essential for α-cell homeostasis.

Dnmt1 活性在 α 细胞中并非必需,但对 α 细胞稳态至关重要

Damond Nicolas, Thorel Fabrizio, Kim Seung K, Herrera Pedro L

Blockade of glucagon signaling prevents or reverses diabetes onset only if residual β-cells persist.

阻断胰高血糖素信号传导只有在残余β细胞持续存在的情况下才能预防或逆转糖尿病的发生

Damond Nicolas, Thorel Fabrizio, Moyers Julie S, Charron Maureen J, Vuguin Patricia M, Powers Alvin C, Herrera Pedro L

A Variant of GJD2, Encoding for Connexin 36, Alters the Function of Insulin Producing β-Cells.

编码连接蛋白 36 的 GJD2 变体改变了产生胰岛素的 β 细胞的功能

Cigliola Valentina, Populaire Celine, Pierri Ciro L, Deutsch Samuel, Haefliger Jacques-Antoine, Fadista João, Lyssenko Valeriya, Groop Leif, Rueedi Rico, Thorel Fabrizio, Herrera Pedro Luis, Meda Paolo

Connective tissue growth factor modulates adult β-cell maturity and proliferation to promote β-cell regeneration in mice

结缔组织生长因子调节成年小鼠β细胞的成熟和增殖,从而促进β细胞再生。

Riley, Kimberly G; Pasek, Raymond C; Maulis, Matthew F; Peek, Jennifer; Thorel, Fabrizio; Brigstock, David R; Herrera, Pedro L; Gannon, Maureen

Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity

Nkx6.1 控制着一个基因调控网络,该网络对于建立和维持胰岛β细胞的特性至关重要。

Schaffer, Ashleigh E; Taylor, Brandon L; Benthuysen, Jacqueline R; Liu, Jingxuan; Thorel, Fabrizio; Yuan, Weiping; Jiao, Yang; Kaestner, Klaus H; Herrera, Pedro L; Magnuson, Mark A; May, Catherine Lee; Sander, Maike

Context-specific α- to-β-cell reprogramming by forced Pdx1 expression

通过强制表达 Pdx1 实现特定情境下的 α 细胞向 β 细胞重编程

Yang, Yu-Ping; Thorel, Fabrizio; Boyer, Daniel F; Herrera, Pedro L; Wright, Christopher V E