日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Stabilization but No Functional Influence of HIF-1α Expression in the Intestinal Epithelium during Salmonella Typhimurium Infection

鼠伤寒沙门氏菌感染期间肠上皮中 HIF-1α 表达保持稳定但没有功能影响

Laura Robrahn, Aline Dupont, Sandra Jumpertz, Kaiyi Zhang, Christian H Holland, Joël Guillaume, Sabrina Rappold, Johanna Roth, Vuk Cerovic, Julio Saez-Rodriguez, Mathias W Hornef, Thorsten Cramer

Deletion of mTOR in liver epithelial cells enhances hepatic metastasis of colon cancer

肝上皮细胞中mTOR的缺失增强结肠癌的肝转移

Long Jiao #, Roman Eickhoff #, Antje Egners, Sandra Jumpertz, Johanna Roth, Merve Erdem, Andreas Kroh, Hans Duimel, Carmen López-Iglesias, Pilar Caro, Lara R Heij, Maximilian Schmeding, David Meierhofer, Ulf P Neumann, Thorsten Cramer

Cyclin E1 in Murine and Human Liver Cancer: A Promising Target for Therapeutic Intervention during Tumour Progression

小鼠和人类肝癌中的细胞周期蛋白 E1:肿瘤进展过程中治疗干预的一个有希望的靶点

Roland Sonntag, Christian Penners, Marlene Kohlhepp, Ute Haas, Daniela Lambertz, Andreas Kroh, Thorsten Cramer, Fabio Ticconi, Ivan G Costa, Frank Tacke, Nikolaus Gassler, Christian Trautwein, Christian Liedtke

Patient-specific logic models of signaling pathways from screenings on cancer biopsies to prioritize personalized combination therapies

通过癌症活检筛查建立针对患者的具体信号通路逻辑模型,优先考虑个性化联合疗法

Federica Eduati, Patricia Jaaks, Jessica Wappler, Thorsten Cramer, Christoph A Merten, Mathew J Garnett, Julio Saez-Rodriguez

Kinetic modelling of quantitative proteome data predicts metabolic reprogramming of liver cancer

定量蛋白质组数据的动力学建模预测肝癌的代谢重编程

Nikolaus Berndt #, Antje Egners #, Guido Mastrobuoni #, Olga Vvedenskaya, Athanassios Fragoulis, Aurélien Dugourd, Sascha Bulik, Matthias Pietzke, Chris Bielow, Rob van Gassel, Steven W Olde Damink, Merve Erdem, Julio Saez-Rodriguez, Hermann-Georg Holzhütter #, Stefan Kempa #, Thorsten Cramer #6

Macrophages protect against loss of adipose tissue during cancer cachexia

巨噬细胞在癌症恶病质期间防止脂肪组织的损失

Merve Erdem, Diana Möckel, Sandra Jumpertz, Cathleen John, Athanassios Fragoulis, Ines Rudolph, Johanna Wulfmeier, Jochen Springer, Henrike Horn, Marco Koch, Georg Lurje, Twan Lammers, Steven Olde Damink, Gregory van der Kroft, Felix Gremse, Thorsten Cramer

A Newly Established Murine Cell Line as a Model for Hepatocellular Cancer in Non-Alcoholic Steatohepatitis

新建立的小鼠细胞系作为非酒精性脂肪性肝炎中肝细胞癌的模型

Andreas Kroh, Jeanette Walter, Herdit Schüler, Jochen Nolting, Roman Eickhoff, Daniel Heise, Ulf Peter Neumann, Thorsten Cramer, Tom Florian Ulmer, Athanassios Fragoulis

A microfluidics platform for combinatorial drug screening on cancer biopsies

用于癌症活检组合药物筛选的微流体平台

Federica Eduati, Ramesh Utharala, Dharanija Madhavan, Ulf Peter Neumann, Thomas Longerich, Thorsten Cramer, Julio Saez-Rodriguez, Christoph A Merten

Widespread Post-transcriptional Attenuation of Genomic Copy-Number Variation in Cancer

癌症中基因组拷贝数变异的广泛转录后衰减

Emanuel Gonçalves, Athanassios Fragoulis, Luz Garcia-Alonso, Thorsten Cramer, Julio Saez-Rodriguez, Pedro Beltrao

HIF1α modulates cell fate reprogramming through early glycolytic shift and upregulation of PDK1-3 and PKM2

HIF1α 通过早期糖酵解转变和 PDK1-3 和 PKM2 的上调来调节细胞命运重编程

Alessandro Prigione, Nadine Rohwer, Sheila Hoffmann, Barbara Mlody, Katharina Drews, Raul Bukowiecki, Katharina Blümlein, Erich E Wanker, Markus Ralser, Thorsten Cramer, James Adjaye