日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Effect of proinflammatory cytokines on intestinal drug transporters in human enteroid monolayers

促炎细胞因子对人肠类器官单层细胞中肠道药物转运蛋白的影响

Wang, Kai; Tsang, Yik Pui; Thummel, Kenneth E; Kelly, Edward J; Mao, Qingcheng; Unadkat, Jashvant D

Human intestinal enteroids: Nonclinical applications for predicting oral drug disposition, toxicity, and efficacy

人类肠道类器官:预测口服药物处置、毒性和疗效的非临床应用

O'Mahony, Eimear T; Arian, Christopher M; Aryeh, Kayenat S; Wang, Kai; Thummel, Kenneth E; Kelly, Edward J

The fate of pyruvate dictates cell growth by modulating cellular redox potential.

丙酮酸的命运通过调节细胞氧化还原电位来决定细胞生长。

Toshniwal Ashish G, Lam Geanette, Bott Alex J, Cluntun Ahmad A, Skabelund Rachel, Nam Hyuck-Jin, Wisidagama Dona R, Thummel Carl S, Rutter Jared

Early clinical evaluation of a vendor developed pediatric artificial intelligence sepsis model in the emergency department

在急诊科对供应商开发的儿科人工智能脓毒症模型进行早期临床评估

Kandaswamy, Swaminathan; Orenstein, Evan W; Muthu, Naveen; McCarter, Andrea; Braykov, Nikolay; Beus, Jonathan M; Ray, Edwin; Senior, Tal; Brown, Sara P; Carter, Rebekah; Gleeson, MaryBeth; Thummel, Hannah; Cheng, John; Bui, Thuy; Blanco, Reena; Hebbar, Kiran; Fortenberry, James; Iyer, Srikant B; Mai, Mark V

Microglia response and function in a chronic model of photoreceptor damage

在慢性光感受器损伤模型中,小胶质细胞的反应和功能

Raghavan, Deepa; Jeakle, Olivia; Berry, Yasmeen; Victor, Majd; Thummel, Ryan

Effect of calcium oxalate microcrystals on kidney proximal tubule epithelial cell gene expression in microgravity

草酸钙微晶对微重力下肾近端小管上皮细胞基因表达的影响

Jones-Isaac, Kendan; Yeung, Catherine K; Bain, Jacelyn; Lidberg, Kevin; Yang, Jade; Wang, Lu; MacDonald, James; Bammler, Theo; Thummel, Kenneth E; Corn, Megan; Ruiz, Micaela Vela; Countryman, Stefanie; Koenig, Paul; Mann, Henning H; Himmelfarb, Jonathan; Kelly, Edward J

Leveraging RNA-seq deconvolution to improve complex in vitro model characterization

利用RNA-seq反卷积技术改进复杂体外模型表征

Hansen, Brad C; Arian, Christopher M; Zeng, Yuting; Takezawa, Meg G; Theberge, Ashleigh B; Faustman, Elaine M; Thummel, Kenneth E; Kelly, Edward J

Vibrio cholerae Gut Colonization of Zebrafish Larvae Induces a Dampened Sensorimotor Response

霍乱弧菌在斑马鱼幼体肠道定植可诱导感觉运动反应减弱

Cubillejo, Isabella; Theis, Kevin R; Panzer, Jonathan; Luo, Xixia; Banerjee, Shreya; Thummel, Ryan; Withey, Jeffrey H

A gut response: Application of human enteroid monolayers to probe the mechanism of the goldenseal-mediated inhibition of metformin intestinal absorption

肠道反应:应用人肠类器官单层细胞探究北美黄连介导的二甲双胍肠道吸收抑制机制

Arian, Christopher M; O'Mahony, Eimear T; Manwill, Preston K; Graf, Tyler N; Oberlies, Nicholas H; Cech, Nadja B; Clarke, John D; Smith, Jason G; Paine, Mary F; Kelly, Edward J; Thummel, Kenneth E

The Pharmacokinetic Interaction Between Metformin and the Natural Product Goldenseal Is Metformin Dose-Dependent: A Three-Arm Crossover Study in Adults With Type 2 Diabetes.

二甲双胍与天然产物金印草之间的药代动力学相互作用与二甲双胍剂量相关:一项针对 2 型糖尿病成年患者的三臂交叉研究

Nguyen James T, Arian Christopher M, Tanna Rakshit S, Cherel Maxey G, Layton Matthew E, White John R, Thummel Kenneth E, Paine Mary F