日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

DualPG-DTA: A Large Language Model-Powered Graph Neural Network Framework for Enhanced Drug-Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting In Vivo Anti-Leukemia Activity

DualPG-DTA：一种基于大型语言模型的图神经网络框架，用于增强药物靶点亲和力预测和发现具有体内抗白血病活性的新型 CDK9 抑制剂。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202513099
Chen, Yihao; Huang, Jindi; Liu, Cong; Zhang, Shipeng; Li, Xinze; Zhang, Zhang; Chen, Tie-Gen; Wang, Ling
白血病
CDK9
发表日期：2026
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The anti-aging potential of VA'S new derivatives through metabolomic profiling

通过代谢组学分析VA新衍生物的抗衰老潜力

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-25545-9
Tan, Li; Wu, Jiang; Wang, Jiewen; Zhang, Hongkang; Zhang, Wei; Gao, Ang; Zhong, Zhijian; Chen, Tie-Gen; Zhou, Baoping; Han, Tengfei; Zhang, Die; He, Miao; Fan, Zhenxin; Zhou, Ya
衰老
代谢
发表日期：2025
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Deoxygenative radical cross-coupling of C(sp(3))-O/C(sp(3))-H bonds promoted by hydrogen-bond interaction

氢键相互作用促进的C(sp(3))-O/C(sp(3))-H键的脱氧自由基交叉偶联

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-024-50897-7
Wang, Yue; Zhang, Suping; Zeng, Ke; Zhang, Pengli; Song, Xiaorong; Chen, Tie-Gen; Xia, Guoqin
发表日期：2024
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Convergent Synthesis of (R)-Silodosin via Decarboxylative Cross-Coupling

通过脱羧交叉偶联反应聚合合成(R)-西洛多辛

期刊:Tetrahedron Letters
影响因子:1.5
doi:10.1016/j.tetlet.2021.153290
Chen, Tie-Gen; Mele, Lucas; Jentzer, Olivier; Delbrayelle, Dominique; Echeverria, Pierre-Georges; Vantourout, Julien C; Baran, Phil S
发表日期：2021
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Quaternary Centers by Nickel-Catalyzed Cross-Coupling of Tertiary Carboxylic Acids and (Hetero)Aryl Zinc Reagents

镍催化叔羧酸与（杂）芳基锌试剂交叉偶联合成季碳中心

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.201814524
Chen, Tie-Gen; Zhang, Haolin; Mykhailiuk, Pavel K; Merchant, Rohan R; Smith, Courtney A; Qin, Tian; Baran, Phil S
发表日期：2019
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Building C(sp(3))-rich complexity by combining cycloaddition and C-C cross-coupling reactions

通过结合环加成反应和C-C交叉偶联反应构建富含C(sp(3))的复杂性

期刊:Nature
影响因子:48.5
doi:10.1038/s41586-018-0391-9
Chen, Tie-Gen; Barton, Lisa M; Lin, Yutong; Tsien, Jet; Kossler, David; Bastida, Iñaki; Asai, Shota; Bi, Cheng; Chen, Jason S; Shan, Mingde; Fang, Hui; Fang, Francis G; Choi, Hyeong-Wook; Hawkins, Lynn; Qin, Tian; Baran, Phil S
发表日期：2018
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Nickel-Catalyzed Cross-Coupling of Redox-Active Esters with Boronic Acids

镍催化氧化还原活性酯与硼酸的交叉偶联反应

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.201605463
Wang, Jie; Qin, Tian; Chen, Tie-Gen; Wimmer, Laurin; Edwards, Jacob T; Cornella, Josep; Vokits, Benjamin; Shaw, Scott A; Baran, Phil S
发表日期：2016
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Magnetic resonance diffusion tensor imaging following major ozonated autohemotherapy for treatment of acute cerebral infarction

急性脑梗死患者接受大量臭氧自体血液疗法后的磁共振弥散张量成像

期刊:Neural Regeneration Research
影响因子:6.7
doi:10.4103/1673-5374.187046
Wu, Xiao-Na; Zhang, Tao; Wang, Jun; Liu, Xiao-Yan; Li, Zhen-Sheng; Xiang, Wei; Du, Wei-Qing; Yang, Hong-Jun; Xiong, Tie-Gen; Deng, Wen-Ting; Peng, Kai-Run; Pan, Su-Yue
神经科学
发表日期：2016
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