日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Genetic Insights into Head-to-Body Ratios Via Deep Learning-Based Image Segmentation and Implications for Common Diseases

基于深度学习的图像分割揭示头身比例的遗传学信息及其对常见疾病的启示

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-67578-8
Shi, Wei; Dong, Shan-Shan; Zhu, Ren-Jie; Tang, Shi-Hao; Wang, Jia-Hao; Jiang, Feng; Wu, Hao; Duan, Yuan-Yuan; Guo, Jing; Liu, Kai; Li, Zheng-Qiang; Li, Meng; Wang, Jianzhong; Guo, Yan; Yang, Tie-Lin
发表日期：2025
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Revealing the genetic architectures underlying organ-specific aging based on proteomic data

基于蛋白质组学数据揭示器官特异性衰老的遗传结构

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-67223-4
Zhu, Ren-Jie; Guo, Yan; Wang, Jia-Hao; Yu, Ke; Shi, Wei; Pan, Wen; Yu, Xian-Lin; Chen, Wei; Dong, Shan-Shan; Yang, Tie-Lin
衰老
发表日期：2025
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Genetic transcriptional regulation profiling of cartilage reveals pathogenesis of osteoarthritis.

软骨基因转录调控谱分析揭示骨关节炎的发病机制

期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2025.105821
Tian Wen, Dong Shan-Shan, Jiang Feng, Zhang Jun-Qi, Wang Chen, He Chang-Yi, Hu Shou-Ye, Hao Ruo-Han, Song Hui-Miao, Gao Hui-Wu, An Ke, Zhu Dong-Li, Yang Zhi, Guo Yan, Yang Tie-Lin
免疫/内分泌
关节炎
转录调控
发表日期：2025
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Blood plasma proteome-wide association study implicates novel proteins in the pathogenesis of multiple cardiovascular diseases

血浆蛋白质组关联研究揭示了多种心血管疾病发病机制中涉及的新蛋白

期刊:Cardiovascular Diabetology
影响因子:10.6
doi:10.1186/s12933-025-02847-w
Wang, Jia-Hao; Dong, Shan-Shan; Huang, Wei; Wang, Hao-An; Liu, Shao-Shan; Ma, Xiaoyi; Zhu, Ren-Jie; Shi, Wei; Wu, Hao; Yu, Ke; Zhang, Tian-Pei; Wang, Cong-Ru; Guo, Yan; Xue, Hanzhong; Yang, Tie-Lin
心血管疾病
心血管
发表日期：2025
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The function of GPCRs in different bone cells

GPCRs在不同骨细胞中的功能

期刊:International Journal of Biological Sciences
影响因子:10
doi:10.7150/ijbs.113585
Zhang, Yan; Wang, Nai-Ning; Qiu, Zi-Han; Wang, Jia-Hao; An, Wen-Na; Shi, Li-Dan; Chen, Fei; Zhang, Da-Jin; Wang, Si-Yue; Yang, Tie-Lin; Hu, Shou-Ye; Guo, Yan
细胞生物学
GPCR/Calcium/cAMP
发表日期：2025
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Systematic functional characterization of non-coding regulatory SNPs associated with central obesity

对与中心性肥胖相关的非编码调控SNP进行系统性功能表征

期刊:American Journal of Human Genetics
影响因子:8.1
doi:10.1016/j.ajhg.2024.11.005
Dong, Shan-Shan; Duan, Yuan-Yuan; Zhu, Ren-Jie; Jia, Ying-Ying; Chen, Jia-Xin; Huang, Xiao-Ting; Tang, Shi-Hao; Yu, Ke; Shi, Wei; Chen, Xiao-Feng; Jiang, Feng; Hao, Ruo-Han; Liu, Yunlong; Liu, Zhongbo; Guo, Yan; Yang, Tie-Lin
信号转导
肥胖
代谢
发表日期：2025
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Long noncoding RNA LINC00339 promotes osteoporosis development via modulating of regulator CDC42 by binding PARP1.

长链非编码RNA LINC00339通过与PARP1结合调节调节因子CDC42，从而促进骨质疏松症的发展

期刊:Non-coding RNA Research
影响因子:4.7
doi:10.1016/j.ncrna.2025.06.004
Zhu Dong-Li, Zhang Yan, Zhang Xiao-Yu, Qiu Zi-Han, Li Ke, Zhou Xiao-Rong, He Zhen-Zhen, Chen Xiao-Feng, Dong Shan-Shan, Tian Wen, Wang Ya-Kang, Yang Tie-Lin, Yang Bo, Guo Yan
骨科研究
PARP1
发表日期：2025
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Review of diffusion models and its applications in biomedical informatics

扩散模型及其在生物医学信息学中的应用综述

期刊:BMC Medical Informatics and Decision Making
影响因子:3.8
doi:10.1186/s12911-025-03210-5
Luo, Jiawei; Yang, Liren; Liu, Yan; Hu, Changbao; Wang, Grant; Yang, Yan; Yang, Tie-Lin; Zhou, Xiaobo
发表日期：2025
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RUNX2 Phase Separation Mediates Long-Range Regulation Between Osteoporosis-Susceptibility Variant and XCR1 to Promote Osteoblast Differentiation

RUNX2 相分离介导骨质疏松易感性变异与 XCR1 之间的远程调控，促进成骨细胞分化

期刊:Advanced Science
影响因子:
doi:10.1002/advs.202413561
Yan Zhang, Xin-Hao Li, Pai Peng, Zi-Han Qiu, Chen-Xi Di, Xiao-Feng Chen, Nai-Ning Wang, Fei Chen, Yin-Wei He, Zhong-Bo Liu, Fan Zhao, Dong-Li Zhu, Shan-Shan Dong, Shou-Ye Hu, Zhi Yang, Yi-Ping Li, Yan Guo, Tie-Lin Yang
免疫
细胞生物学
骨质疏松
其它细胞
SP7
发表日期：2025
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Revealing brain cell-stratified causality through dissecting causal variants according to their cell-type-specific effects on gene expression

通过根据致病变异对基因表达的细胞类型特异性影响对其进行解剖，揭示脑细胞分层因果关系

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-024-49263-4
Hao, Ruo-Han; Zhang, Tian-Pei; Jiang, Feng; Liu, Jun-Hui; Dong, Shan-Shan; Li, Meng; Guo, Yan; Yang, Tie-Lin
细胞生物学
神经科学
发表日期：2024
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