Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action
Affimer蛋白通过竞争性和变构作用方式,以高特异性抑制免疫复合物与FcγRIIIa的结合。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1707856115
Robinson, James I; Baxter, Euan W; Owen, Robin L; Thomsen, Maren; Tomlinson, Darren C; Waterhouse, Mark P; Win, Stephanie J; Nettleship, Joanne E; Tiede, Christian; Foster, Richard J; Owens, Raymond J; Fishwick, Colin W G; Harris, Sarah A; Goldman, Adrian; McPherson, Michael J; Morgan, Ann W