日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Presentation of the protective epitope in a Chlamydia muridarum MOMP vaccine is dependent on γ-interferon-inducible lysosomal thiol reductase (GILT)

鼠衣原体 MOMP 疫苗中保护性表位的呈现依赖于 γ-干扰素诱导的溶酶体硫醇还原酶 (GILT)

Pal, Sukumar; Johnson, Raymond M; Tifrea, Delia F; Cresswell, Peter; de la Maza, Luis M

Safe immunosuppression-resistant pan-cancer immunotherapeutics by velcro-like density-dependent targeting of tumor-associated carbohydrate antigens.

通过类似尼龙搭扣的密度依赖性靶向肿瘤相关碳水化合物抗原,实现安全、抗免疫抑制的泛癌免疫疗法。

Zhou Raymond W, Purohit Paresh Kumar, Kim Jai Hyun, Lee Sung-Uk, Burshteyn Nicole, Tifrea Delia, Cordon Andres, Grigorian Ani, Newton Barbara L, Edwards Robert A, Demetriou Michael

Human CD4 T cells are a functional target for lipid nanoparticle-based mRNA vaccines

人类CD4 T细胞是基于脂质纳米颗粒的mRNA疫苗的功能性靶点。

Kim, Samuel C; Felgner, Jiin; Soto, Mariella S; Hitchcock, Lauren; Silzel, Emily K; Beares, Haven; Hwang, Michael J; Yates, Timothy B; Cheng, Siyuan; Joloya, Erika M; Sureshchandra, Suhas; Sorn, Andrew M; Wagoner, Zachary W; Tifrea, Delia; Kabeer, Mustafa; Trask, Douglas; Othy, Shivashankar; Felgner, Philip; Wagar, Lisa E

Insights into Persistent SARS-CoV-2 Reservoirs in Chronic Long COVID

慢性新冠患者体内持续存在的SARS-CoV-2病毒库的见解

Prakash, Swayam; Karan, Sweta; Lekbach, Yassir; Tifrea, Delia F; Figueroa, Cesar J; Ulmer, Jeffrey B; Young, James F; Glenn, Greg; Gil, Daniel; Jones, Trevor M; Redfield, Robert R; BenMohamed, Lbachir

Chlamydia trachomatis Serovars from the C-Complex and the B- and C-Related Complexes Are Significantly More Pathogenic than Those from the B-Complex in C3H/HeN but Not in BALB/c Mice

在C3H/HeN小鼠中,来自C复合体和B及C相关复合体的沙眼衣原体血清型比来自B复合体的血清型致病性显著更高,但在BALB/c小鼠中则不然。

Pal, Sukumar; Carmichael, Jennifer R; Tifrea, Delia F; Tatarenkova, Olga; de la Maza, Luis M

Cross-protection induced by highly conserved human B, CD4(+), and CD8(+) T-cell epitopes-based vaccine against severe infection, disease, and death caused by multiple SARS-CoV-2 variants of concern

基于高度保守的人类B细胞、CD4(+)和CD8(+)T细胞表位的疫苗可诱导交叉保护,预防多种SARS-CoV-2变异株引起的严重感染、疾病和死亡。

Prakash, Swayam; Dhanushkodi, Nisha R; Zayou, Latifa; Ibraim, Izabela Coimbra; Quadiri, Afshana; Coulon, Pierre Gregoire; Tifrea, Delia F; Suzer, Berfin; Shaik, Amin Mohammed; Chilukuri, Amruth; Edwards, Robert A; Singer, Mahmoud; Vahed, Hawa; Nesburn, Anthony B; Kuppermann, Baruch D; Ulmer, Jeffrey B; Gil, Daniel; Jones, Trevor M; BenMohamed, Lbachir

High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4+ and CD8+ memory T cells are associated with protection from symptomatic and fatal SARS-CoV-2 infections in unvaccinated COVID-19 patients

在未接种疫苗的 COVID-19 患者中,高频率的 α 普通感冒冠状病毒/SARS-CoV-2 交叉反应功能性 CD4+ 和 CD8+ 记忆 T 细胞与预防有症状和致命的 SARS-CoV-2 感染有关

Pierre-Gregoire Coulon #, Swayam Prakash #, Nisha R Dhanushkodi, Ruchi Srivastava, Latifa Zayou, Delia F Tifrea, Robert A Edwards, Cesar J Figueroa, Sebastian D Schubl, Lanny Hsieh, Anthony B Nesburn, Baruch D Kuppermann, Elmostafa Bahraoui, Hawa Vahed, Daniel Gil, Trevor M Jones, Jeffrey B Ulmer, L

Colorectal Cancer Stem Cell Subtypes Orchestrate Distinct Tumor Microenvironments

结直肠癌干细胞亚型调控不同的肿瘤微环境

Linzi Hosohama, Delia F Tifrea, Kevin Nee, Sung Yun Park, Jie Wu, Amber N Habowski, Cassandra Van, Marcus M Seldin, Robert A Edwards, Marian L Waterman

A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster Model

基于广谱多抗原 mRNA/LNP 的泛冠状病毒疫苗在叙利亚仓鼠模型中诱导了针对高致病性和严重刺突突变的 SARS-CoV-2 变体引起的感染和疾病的强效交叉保护性免疫

Swayam Prakash, Nisha R Dhanushkodi, Mahmoud Singer, Afshana Quadiri, Latifa Zayou, Hawa Vahed, Pierre-Gregoire Coulon, Izabela Coimbra Ibraim, Christine Tafoya, Lauren Hitchcock, Gary Landucci, Donald N Forthal, Assia El Babsiri, Delia F Tifrea, Cesar J Figueroa, Anthony B Nesburn, Baruch D Kupperm

The Hippo pathway noncanonically drives autophagy and cell survival in response to energy stress

Hippo通路以非经典的方式驱动自噬和细胞存活,以应对能量压力。

Gayoung Seo ,Clinton Yu ,Han Han ,Li Xing ,Rebecca Elizabeth Kattan ,Jeongmin An ,Amrutha Kizhedathu ,Bing Yang ,Annabella Luo ,Abigail L Buckle ,Delia Tifrea ,Robert Edwards ,Lan Huang ,Huai-Qiang Ju ,Wenqi Wang