A proteogenomic gene signature defines prognostic subgroups highlighting PI3K/AKT/mTOR signaling pathway as a therapeutic vulnerability in myeloid malignancies
蛋白质基因组学特征定义了预后亚组,突显了PI3K/AKT/mTOR信号通路在髓系恶性肿瘤治疗中的脆弱性。
期刊:Cell Communication and Signaling
影响因子:8.9
doi:10.1186/s12964-025-02568-3
He, Fan; Lin, Shuyang; Gao, Bei; Ramesh, Varun; Kim, Alexander B; Kong, Tim; Fisher, Daniel A C; Letson, Christopher T; Brakhane, Molly; Fulbright, Mary; Yu, Yanbo; Sardiello, Marco; Di Paola, Jorge; Sykes, Stephen M; Oh, Stephen T