Overexpression of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase A in nerve cells confers resistance to amyloid β and other toxins by decreasing mitochondrial respiration and reactive oxygen species production

神经细胞中丙酮酸脱氢酶激酶 1 和乳酸脱氢酶 A 的过度表达通过降低线粒体呼吸和活性氧的产生来产生对淀粉样蛋白 β 和其他毒素的抵抗力