日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The β3-integrin endothelial adhesome regulates microtubule-dependent cell migration

β3整合素内皮粘附体调节微管依赖性细胞迁移

Samuel J Atkinson, Aleksander M Gontarczyk, Abdullah Aa Alghamdi, Tim S Ellison, Robert T Johnson, Wesley J Fowler, Benjamin M Kirkup, Bernardo C Silva, Bronwen E Harry, Jochen G Schneider, Katherine N Weilbaecher, Mette M Mogensen, Mark D Bass, Maddy Parsons, Dylan R Edwards, Stephen D Robinson

Suppression of β3-integrin in mice triggers a neuropilin-1-dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis

抑制小鼠体内的 β3 整合素会引发神经纤毛蛋白 1 依赖的粘着斑重塑变化,这种变化可以作为阻断病理性血管生成的靶点

Tim S Ellison, Samuel J Atkinson, Veronica Steri, Benjamin M Kirkup, Michael E J Preedy, Robert T Johnson, Christiana Ruhrberg, Dylan R Edwards, Jochen G Schneider, Katherine Weilbaecher, Stephen D Robinson