Rac-1 superactivation triggers insulin-independent glucose transporter 4 (GLUT4) translocation that bypasses signaling defects exerted by c-Jun N-terminal kinase (JNK)- and ceramide-induced insulin resistance

Rac-1 超活化会触发胰岛素非依赖性葡萄糖转运蛋白 4 (GLUT4) 易位，从而绕过由 c-Jun N 端激酶 (JNK) 和神经酰胺诱导的胰岛素抵抗引起的信号传导缺陷