日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The lncRNA HOXA11os regulates mitochondrial function in myeloid cells to maintain intestinal homeostasis

lncRNA HOXA11os 调节髓系细胞的线粒体功能以维持肠道稳态

Liraz Shmuel-Galia, Fiachra Humphries, Tim Vierbuchen, Zhaozhao Jiang, Nolan Santos, John Johnson, Boris Shklyar, Leonel Joannas, Nicholas Mustone, Shany Sherman, Doyle Ward, JeanMarie Houghton, Christina E Baer, Aisling O'Hara, Jorge Henao-Mejia, Kasper Hoebe, Katherine A Fitzgerald

The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2

lncRNA LUCAT1 在炎症性疾病中升高,并通过调节 NR4A2 的剪接和稳定性来抑制炎症

Tim Vierbuchen, Shiuli Agarwal, John L Johnson, Liraz Galia, Xuqiu Lei, Karina Stein, David Olagnier, Karoline I Gaede, Christian Herzmann, Christian K Holm, Holger Heine, Athma Pai, Aisling O'Hara Hall, Kasper Hoebe, Katherine A Fitzgerald

Epithelial HNF4A shapes the intraepithelial lymphocyte compartment via direct regulation of immune signaling molecules

上皮细胞HNF4A通过直接调节免疫信号分子来塑造上皮内淋巴细胞区室。

Xuqiu Lei ,Natalia Ketelut-Carneiro ,Liraz Shmuel-Galia ,Weili Xu ,Ruth Wilson ,Tim Vierbuchen ,Yongzhi Chen ,Andrea Reboldi ,Joonsoo Kang ,Karen L Edelblum ,Doyle Ward ,Katherine A Fitzgerald

WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis

结核分枝杆菌利用 WNT6/ACC2 诱导的巨噬细胞三酰甘油储存

Julius Brandenburg, Sebastian Marwitz, Simone C Tazoll, Franziska Waldow, Barbara Kalsdorf, Tim Vierbuchen, Thomas Scholzen, Annette Gross, Svenja Goldenbaum, Alexandra Hölscher, Martina Hein, Lara Linnemann, Maja Reimann, Andreas Kispert, Michael Leitges, Jan Rupp, Christoph Lange, Stefan Niemann, 

Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis

中性粒细胞胞外陷阱相关RNA和LL37促进银屑病中的自我放大炎症

Franziska Herster ,Zsofia Bittner ,Nathan K Archer ,Sabine Dickhöfer ,David Eisel ,Tatjana Eigenbrod ,Thomas Knorpp ,Nicole Schneiderhan-Marra ,Markus W Löffler ,Hubert Kalbacher ,Tim Vierbuchen ,Holger Heine ,Lloyd S Miller ,Dominik Hartl ,Lukas Freund ,Knut Schäkel ,Martin Heister ,Kamran Ghoreschi ,Alexander N R Weber

The long non-coding RNA LUCAT1 is a negative feedback regulator of interferon responses in humans

长链非编码RNA LUCAT1是人类干扰素反应的负反馈调节因子。

Shiuli Agarwal ,Tim Vierbuchen ,Sreya Ghosh ,Jennie Chan ,Zhaozhao Jiang ,Richard K Kandasamy ,Emiliano Ricci ,Katherine A Fitzgerald

2'- O-methylation within prokaryotic and eukaryotic tRNA inhibits innate immune activation by endosomal Toll-like receptors but does not affect recognition of whole organisms

原核和真核 tRNA 中的 2'-O-甲基化可抑制内体 Toll 样受体的先天免疫激活,但不影响整个生物体的识别

Isabel Freund, Daniel K Buhl, Sébastien Boutin, Annika Kotter, Florian Pichot, Virginie Marchand, Tim Vierbuchen, Holger Heine, Yuri Motorin, Mark Helm, Alexander H Dalpke, Tatjana Eigenbrod

The Human-Associated Archaeon Methanosphaera stadtmanae Is Recognized through Its RNA and Induces TLR8-Dependent NLRP3 Inflammasome Activation

与人类相关的古菌 Methanosphaera stadtmanae 通过其 RNA 被识别并诱导 TLR8 依赖的 NLRP3 炎症小体激活

Tim Vierbuchen, Corinna Bang, Hanna Rosigkeit, Ruth A Schmitz, Holger Heine