Tat expression led to increased histone 3 tri-methylation at lysine 27 and contributed to HIV latency in astrocytes through regulation of MeCP2 and Ezh2 expression
Tat表达导致组蛋白H3第27位赖氨酸三甲基化水平升高,并通过调控MeCP2和Ezh2的表达促进星形胶质细胞中HIV的潜伏感染。
期刊:Journal of Neurovirology
影响因子:1.9
doi:10.1007/s13365-019-00751-0
Liu, Ying; Niu, Yinghua; Li, Lu; Timani, Khalid A; He, Victor L; Sanburns, Chris; Xie, Jiafeng; He, Johnny J
胶质细胞
表观遗传
HIV
信号转导
炎症/感染
微生物学
细胞生物学