Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration.
BRAFV600E 驱动的肿瘤发生需要继发突变来克服其对 RAC1 和迁移的反馈抑制
期刊:Cancer Research
影响因子:16.6
doi:10.1158/0008-5472.CAN-24-2220
Gadal Sunyana, Boyer Jacob A, Roy Simon F, Outmezguine Noah A, Sharma Malvika, Li Hongyan, Fan Ning, Chan Eric, Romin Yevgeniy, Barlas Afsar, Chang Qing, Pancholi Priya, Timaul Neilawattie Merna, Overholtzer Michael, Yaeger Rona, Manova-Todorova Katia, de Stanchina Elisa, Bosenberg Marcus W, Rosen Neal
