日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways.

钙/钙调蛋白依赖性蛋白激酶 II 将内质网应激与 Fas 和线粒体凋亡途径联系起来

Timmins Jenelle M, Ozcan Lale, Seimon Tracie A, Li Gang, Malagelada Cristina, Backs Johannes, Backs Thea, Bassel-Duby Rhonda, Olson Eric N, Anderson Mark E, Tabas Ira

Signal transducer and activator of transcription-1 is critical for apoptosis in macrophages subjected to endoplasmic reticulum stress in vitro and in advanced atherosclerotic lesions in vivo

信号转导和转录激活因子-1 (STAT1) 在体外内质网应激条件下巨噬细胞的凋亡以及体内晚期动脉粥样硬化病变中的凋亡中起着关键作用。

Lim, Wah-Seng; Timmins, Jenelle M; Seimon, Tracie A; Sadler, Anthony; Kolodgie, Frank D; Virmani, Renu; Tabas, Ira

Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages

巨噬细胞特异性Abca1敲除小鼠体内细胞内游离胆固醇增加,增强巨噬细胞的促炎反应。

Zhu, Xuewei; Lee, Ji-Young; Timmins, Jenelle M; Brown, J Mark; Boudyguina, Elena; Mulya, Anny; Gebre, Abraham K; Willingham, Mark C; Hiltbold, Elizabeth M; Mishra, Nilamadhab; Maeda, Nobuyo; Parks, John S

Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I

肝脏 Abca1 的靶向失活会导致严重的低α脂蛋白血症和肾脏载脂蛋白A-I (apoA-I) 的高分解代谢。

Timmins, Jenelle M; Lee, Ji-Young; Boudyguina, Elena; Kluckman, Kimberly D; Brunham, Liam R; Mulya, Anny; Gebre, Abraham K; Coutinho, Jonathan M; Colvin, Perry L; Smith, Thomas L; Hayden, Michael R; Maeda, Nobuyo; Parks, John S