Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I
肝脏 Abca1 的靶向失活会导致严重的低α脂蛋白血症和肾脏载脂蛋白A-I (apoA-I) 的高分解代谢。
期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI23915
Timmins, Jenelle M; Lee, Ji-Young; Boudyguina, Elena; Kluckman, Kimberly D; Brunham, Liam R; Mulya, Anny; Gebre, Abraham K; Coutinho, Jonathan M; Colvin, Perry L; Smith, Thomas L; Hayden, Michael R; Maeda, Nobuyo; Parks, John S