日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Probing binding and cellular activity of pyrrolidinone and piperidinone small molecules targeting the urokinase receptor

探究吡咯烷酮和哌啶酮小分子针对尿激酶受体的结合和细胞活性

Timmy Mani, Degang Liu, Donghui Zhou, Liwei Li, William Eric Knabe, Fang Wang, Kyungsoo Oh, Samy O Meroueh

Small-molecule inhibition of the uPAR·uPA interaction: synthesis, biochemical, cellular, in vivo pharmacokinetics and efficacy studies in breast cancer metastasis

小分子抑制uPAR·uPA相互作用:乳腺癌转移的合成、生化、细胞、体内药代动力学和疗效研究

Timmy Mani, Fang Wang, William Eric Knabe, Anthony L Sinn, May Khanna, Inha Jo, George E Sandusky, George W Sledge Jr, David R Jones, Rajesh Khanna, Karen E Pollok, Samy O Meroueh

Design, synthesis, biochemical studies, cellular characterization, and structure-based computational studies of small molecules targeting the urokinase receptor

针对尿激酶受体的小分子的设计、合成、生化研究、细胞表征和基于结构的计算研究

Fang Wang, W Eric Knabe, Liwei Li, Inha Jo, Timmy Mani, Hartmut Roehm, Kyungsoo Oh, Jing Li, May Khanna, Samy O Meroueh

FERM domain phosphoinositide binding targets merlin to the membrane and is essential for its growth-suppressive function

FERM 结构域磷酸肌醇结合靶向 Merlin 到膜上,对其生长抑制功能至关重要

Timmy Mani, Robert F Hennigan, Lauren A Foster, Deborah G Conrady, Andrew B Herr, Wallace Ip