BYON4228 is a pan-allelic antagonistic SIRPα antibody that potentiates destruction of antibody-opsonized tumor cells and lacks binding to SIRPγ on T cells
BYON4228 是一种泛等位基因拮抗性 SIRPα 抗体，可增强抗体包被的肿瘤细胞的杀伤作用，且不与 T 细胞上的 SIRPγ 结合。
期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2022-006567
van Helden, Mary J; Zwarthoff, Seline A; Arends, Roel J; Reinieren-Beeren, Inge M J; Paradé, Marc C B C; Driessen-Engels, Lilian; de Laat-Arts, Karin; Damming, Désirée; Santegoeds-Lenssen, Ellen W H; van Kuppeveld, Daphne W J; Lodewijks, Imke; Olsman, Hugo; Matlung, Hanke L; Franke, Katka; Mattaar-Hepp, Ellen; Stokman, Marloes E M; de Wit, Benny; Glaudemans, Dirk H R F; van Wijk, Daniëlle E J W; Joosten-Stoffels, Lonnie; Schouten, Jan; Boersema, Paul J; van der Vleuten, Monique; Sanderink, Jorien W H; Kappers, Wendela A; van den Dobbelsteen, Diels; Timmers, Marco; Ubink, Ruud; Rouwendal, Gerard J A; Verheijden, Gijs; van der Lee, Miranda M C; Dokter, Wim H A; van den Berg, Timo K
