日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

In Vivo Labeling Resolves Distinct Temporal, Spatial, and Functional Properties of Tumor Macrophages and Identifies Subset-Specific Effects of PD-L1 Blockade

体内标记解析了肿瘤巨噬细胞不同的时间、空间和功能特性,并识别了PD-L1阻断的亚群特异性效应

Colin Y C Lee,Isaac Dean,Nathan Richoz,Zhi Li,Bethany C Kennedy,Lisa A Vettore,Youhani Samarakoon,Kathryn L Gilroy,Tetsuo Hasegawa,Gianluca Carlesso,Scott A Hammond,Simon J Dovedi,Owen J Sansom,Zewen K Tuong,Timotheus Y F Halim,David R Withers,Menna R Clatworthy

Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance

衰老诱导的内皮细胞表型是免疫介导的衰老监测的基础

Kelvin Yin ,Daniel Patten ,Sarah Gough ,Susana de Barros Gonçalves ,Adelyne Chan ,Ioana Olan ,Liam Cassidy ,Marta Poblocka ,Haoran Zhu ,Aaron Lun ,Martijn Schuijs ,Andrew Young ,Celia Martinez-Jimenez ,Timotheus Y F Halim ,Shishir Shetty ,Masashi Narita ,Matthew Hoare

Early Neutrophilia Marked by Aerobic Glycolysis Sustains Host Metabolism and Delays Cancer Cachexia

以有氧糖酵解为标志的早期中性粒细胞增多症可维持宿主代谢并延缓癌症恶病质

Michele Petruzzelli, Miriam Ferrer, Martijn J Schuijs, Sam O Kleeman, Nicholas Mourikis, Zoe Hall, David Perera, Shwethaa Raghunathan, Michele Vacca, Edoardo Gaude, Michael J Lukey, Duncan I Jodrell, Christian Frezza, Erwin F Wagner, Ashok R Venkitaraman, Timotheus Y F Halim, Tobias Janowitz

Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors

对 Brca1 相关乳腺肿瘤发生过程的时间分辨单细胞分析揭示了管腔祖细胞的异常分化

Karsten Bach # ,Sara Pensa # ,Marija Zarocsinceva ,Katarzyna Kania ,Julie Stockis ,Silvain Pinaud ,Kyren A Lazarus ,Mona Shehata ,Bruno M Simões ,Alice R Greenhalgh ,Sacha J Howell ,Robert B Clarke ,Carlos Caldas ,Timotheus Y F Halim ,John C Marioni ,Walid T Khaled

Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells

组织特异性适应性2型免疫是由2型固有淋巴细胞上共刺激分子OX40L的表达调控的。

Timotheus Y F Halim ,Batika M J Rana ,Jennifer A Walker ,Bernhard Kerscher ,Martin D Knolle ,Helen E Jolin ,Eva M Serrao ,Liora Haim-Vilmovsky ,Sarah A Teichmann ,Hans-Reimer Rodewald ,Marina Botto ,Timothy J Vyse ,Padraic G Fallon ,Zhi Li ,David R Withers ,Andrew N J McKenzie

Group 2 innate lymphoid cells are critical for the initiation of adaptive T helper 2 cell-mediated allergic lung inflammation

第 2 组先天淋巴细胞对于启动适应性 T 辅助细胞 2 介导的过敏性肺部炎症至关重要

Timotheus Y F Halim, Catherine A Steer, Laura Mathä, Matthew J Gold, Itziar Martinez-Gonzalez, Kelly M McNagny, Andrew N J McKenzie, Fumio Takei