Engineered phage with antibacterial CRISPR-Cas selectively reduce E. coli burden in mice
经基因工程改造的噬菌体利用抗菌CRISPR-Cas系统选择性地降低小鼠体内大肠杆菌的数量。
期刊:Nature Biotechnology
影响因子:33.1
doi:10.1038/s41587-023-01759-y
Yilmaz Emre Gencay #,Džiuginta Jasinskytė #,Camille Robert #,Szabolcs Semsey #,Virginia Martínez #,Anders Østergaard Petersen #,Katja Brunner,Ana de Santiago Torio,Alex Salazar,Iszabela Cristiana Turcu,Melissa Kviesgaard Eriksen,Lev Koval,Adam Takos,Ricardo Pascal,Thea Staffeldt Schou,Lone Bayer,Tina Bryde,Katja Chandelle Johansen,Emilie Glad Bak,Frenk Smrekar,Timothy B Doyle,Michael J Satlin,Aurelie Gram,Joana Carvalho,Lene Jessen,Björn Hallström,Jonas Hink,Birgitte Damholt,Alice Troy,Mette Grove,Jasper Clube,Christian Grøndahl,Jakob Krause Haaber,Eric van der Helm,Milan Zdravkovic,Morten Otto Alexander Sommer
