日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer

莫能菌素及其类似物在癌症类器官模型中的抗胶质母细胞瘤活性

Alicja Urbaniak, Megan R Reed, Billie Heflin, John Gaydos, Sergio Piña-Oviedo, Marta Jędrzejczyk, Greta Klejborowska, Natalia Stępczyńska, Timothy C Chambers, Alan J Tackett, Analiz Rodriguez, Adam Huczyński, Robert L Eoff, Angus M MacNicol

Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways

原发性急性淋巴细胞白血病细胞易通过不同的细胞死亡途径在 G1 和 M 期发生微管解聚

Magdalena Delgado, Randall R Rainwater, Billie Heflin, Alicja Urbaniak, Kaitlynn Butler, Mari Davidson, Reine M Protacio, Giulia Baldini, Andrea Edwards, Megan R Reed, Kevin D Raney, Timothy C Chambers

Single and double modified salinomycin analogs target stem-like cells in 2D and 3D breast cancer models

单、双修饰盐霉素类似物靶向二维和三维乳腺癌模型中的干细胞

Alicja Urbaniak, Megan R Reed, Daniel Fil, Anika Moorjani, Sarah Heflin, Michał Antoszczak, Michał Sulik, Adam Huczyński, Michalina Kupsik, Robert L Eoff, Melanie C MacNicol, Timothy C Chambers, Angus M MacNicol

Phosphoproteomics Provides Novel Insights into the Response of Primary Acute Lymphoblastic Leukemia Cells to Microtubule Depolymerization in G1 Phase of the Cell Cycle

磷酸化蛋白质组学为原发性急性淋巴细胞白血病细胞对细胞周期 G1 期微管解聚的反应提供了新的见解

Magdalena Delgado, Charity L Washam, Alicja Urbaniak, Billie Heflin, Aaron J Storey, Renny S Lan, Samuel G Mackintosh, Alan J Tackett, Stephanie D Byrum, Timothy C Chambers

Carbamate derivatives of colchicine show potent activity towards primary acute lymphoblastic leukemia and primary breast cancer cells-in vitro and ex vivo study

秋水仙碱的氨基甲酸酯衍生物对原发性急性淋巴细胞白血病和原发性乳腺癌细胞表现出强效活性-体外和离体研究

Alicja Urbaniak, Fariba Jousheghany, Sergio Piña-Oviedo, Youzhong Yuan, Urszula Majcher-Uchańska, Greta Klejborowska, Anika Moorjani, Behjatolah Monzavi-Karbassi, Adam Huczyński, Timothy C Chambers

The response of phyllodes tumor of the breast to anticancer therapy: An in vitro and ex vivo study

乳腺叶状肿瘤对抗癌治疗的反应:一项体外和离体研究

Alicja Urbaniak ,Fariba Jousheghany ,Youzhong Yuan ,Sergio Piña-Oviedo ,Adam Huczyński ,Magdalena Delgado ,Thomas Kieber-Emmons ,Behjatolah Monzavi-Karbassi ,Timothy C Chambers

Microtubules play an essential role in the survival of primary acute lymphoblastic leukemia cells advancing through G1 phase

微管在原发性急性淋巴细胞白血病细胞进入 G1 期的过程中发挥着至关重要的作用

Magdalena Delgado, Timothy C Chambers

Mitotic arrest-induced phosphorylation of Mcl-1 revisited using two-dimensional gel electrophoresis and phosphoproteomics: nine phosphorylation sites identified

使用二维凝胶电泳和磷酸化蛋白质组学重新审视有丝分裂停滞诱导的 Mcl-1 磷酸化:鉴定出 9 个磷酸化位点

Rong Chu, Sarah E Alford, Katherine Hart, Anisha Kothari, Samuel G Mackintosh, Matthew R Kovak, Timothy C Chambers

Molecular analysis of functional redundancy among anti-apoptotic Bcl-2 proteins and its role in cancer cell survival

抗凋亡 Bcl-2 蛋白功能冗余的分子分析及其在癌细胞存活中的作用

Joshua M Eichhorn, Sarah E Alford, Nandini Sakurikar, Timothy C Chambers

Cyclin B1 overexpression induces cell death independent of mitotic arrest

细胞周期蛋白B1过度表达诱导细胞死亡,而不依赖于有丝分裂停滞

Joshua M Eichhorn, Anisha Kothari, Timothy C Chambers