日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CTLA-4Ig (abatacept) balances bone anabolic effects of T cells and Wnt-10b with antianabolic effects of osteoblastic sclerostin

CTLA-4Ig(阿巴西普)平衡 T 细胞和 Wnt-10b 的骨合成代谢作用与成骨细胞硬化蛋白的抗合成代谢作用

Susanne Roser-Page, Tatyana Vikulina, Daiana Weiss, Mark M Habib, George R Beck Jr, Roberto Pacifici, Timothy F Lane, M Neale Weitzmann

NOTCH1 is a mechanosensor in adult arteries

NOTCH1 是成人动脉中的机械传感器

Julia J Mack, Thiago S Mosqueiro, Brian J Archer, William M Jones, Hannah Sunshine, Guido C Faas, Anais Briot, Raquel L Aragón, Trent Su, Milagros C Romay, Austin I McDonald, Cheng-Hsiang Kuo, Carlos O Lizama, Timothy F Lane, Ann C Zovein, Yun Fang, Elizabeth J Tarling, Thomas Q de Aguiar Vallim, Mo

Erythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling

通过促红细胞生成素独立的 AKT 信号传导,人类胚胎干细胞进行红细胞生成

William S Kim, Yuhua Zhu, Qiming Deng, Chee Jia Chin, Chong Bin He, Amanda J Grieco, Gautam G Dravid, Chintan Parekh, Roger P Hollis, Timothy F Lane, Eric E Bouhassira, Donald B Kohn, Gay M Crooks

PIAS1 regulates breast tumorigenesis through selective epigenetic gene silencing

PIAS1 通过选择性表观遗传基因沉默调控乳腺肿瘤发生

Bin Liu, Samuel Tahk, Kathleen M Yee, Randy Yang, Yonghui Yang, Ryan Mackie, Cary Hsu, Vasili Chernishof, Neil O'Brien, Yusheng Jin, Guoping Fan, Timothy F Lane, Jianyu Rao, Dennis Slamon, Ke Shuai

PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response

PPM1l 编码肌醇需要蛋白 1 (IRE1) 特异性磷酸酶,可调节 ER 应激反应的功能结果

Gang Lu, Asuka Ota, Shuxun Ren, Sarah Franklin, Christoph D Rau, Peipei Ping, Timothy F Lane, Z Hong Zhou, Karen Reue, Aldons J Lusis, Thomas Vondriska, Yibin Wang

Cooperation between Pik3ca and p53 mutations in mouse mammary tumor formation

Pik3ca 和 p53 突变在小鼠乳腺肿瘤形成中的协同作用

Jessica R Adams, Keli Xu, Jeff C Liu, Natalia M Ruiz Agamez, Amanda J Loch, Ruth G Wong, Wei Wang, Katherine L Wright, Timothy F Lane, Eldad Zacksenhaus, Sean E Egan

Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status

小鼠乳腺祖细胞中的 Rb 缺失会诱导管腔 B 或基底样/EMT 肿瘤亚型,具体取决于 p53 状态

Zhe Jiang, Tao Deng, Robert Jones, Huiqin Li, Jason I Herschkowitz, Jeff C Liu, Victor J Weigman, Ming-Sound Tsao, Timothy F Lane, Charles M Perou, Eldad Zacksenhaus

Wnt10b deficiency results in age-dependent loss of bone mass and progressive reduction of mesenchymal progenitor cells

Wnt10b 缺乏导致年龄依赖性的骨量损失和间充质祖细胞逐渐减少

Jennifer R Stevens, Gustavo A Miranda-Carboni, Meredith A Singer, Sean M Brugger, Karen M Lyons, Timothy F Lane

Molecular properties of CD133+ glioblastoma stem cells derived from treatment-refractory recurrent brain tumors

源自治疗难治性复发性脑肿瘤的 CD133+ 胶质母细胞瘤干细胞的分子特性

Qinghai Liu, David H Nguyen, Qinghua Dong, Peter Shitaku, Kenneth Chung, On Ying Liu, Jonathan L Tso, Jason Y Liu, Veerauo Konkankit, Timothy F Cloughesy, Paul S Mischel, Timothy F Lane, Linda M Liau, Stanley F Nelson, Cho-Lea Tso

Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival

雌激素通过诱导成骨细胞中的 Fas 配体来调节破骨细胞的存活,从而保护骨骼

Susan A Krum, Gustavo A Miranda-Carboni, Peter V Hauschka, Jason S Carroll, Timothy F Lane, Leonard P Freedman, Myles Brown