日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeted replacement of full-length CFTR in human airway stem cells by CRISPR-Cas9 for pan-mutation correction in the endogenous locus

利用 CRISPR-Cas9 技术靶向替换人呼吸道干细胞中的全长 CFTR 基因,以纠正内源性基因位点的泛突变

Sriram Vaidyanathan ,Ron Baik ,Lu Chen ,Dawn T Bravo ,Carlos J Suarez ,Shayda M Abazari ,Ameen A Salahudeen ,Amanda M Dudek ,Christopher A Teran ,Timothy H Davis ,Ciaran M Lee ,Gang Bao ,Scott H Randell ,Steven E Artandi ,Jeffrey J Wine ,Calvin J Kuo ,Tushar J Desai ,Jayakar V Nayak ,Zachary M Sellers ,Matthew H Porteus

Comprehensive analysis and accurate quantification of unintended large gene modifications induced by CRISPR-Cas9 gene editing

全面分析并准确量化 CRISPR-Cas9 基因编辑引起的意外大型基因修饰

So Hyun Park, Mingming Cao, Yidan Pan, Timothy H Davis, Lavanya Saxena, Harshavardhan Deshmukh, Yilei Fu, Todd Treangen, Vivien A Sheehan, Gang Bao

Electrocorticography and stereo EEG provide distinct measures of brain connectivity: implications for network models

脑电皮层图和立体脑电图提供了不同的脑连接测量方法:对网络模型的启示

Bernabei, John M; Arnold, T Campbell; Shah, Preya; Revell, Andrew; Ong, Ian Z; Kini, Lohith G; Stein, Joel M; Shinohara, Russell T; Lucas, Timothy H; Davis, Kathryn A; Bassett, Danielle S; Litt, Brian

AAV-CRISPR Gene Editing Is Negated by Pre-existing Immunity to Cas9

由于对 Cas9 具有预先存在的免疫力,AAV-CRISPR 基因编辑无法进行

Ang Li, Mark R Tanner, Ciaran M Lee, Ayrea E Hurley, Marco De Giorgi, Kelsey E Jarrett, Timothy H Davis, Alexandria M Doerfler, Gang Bao, Christine Beeton, William R Lagor

Highly efficient editing of the β-globin gene in patient-derived hematopoietic stem and progenitor cells to treat sickle cell disease

高效编辑患者来源的造血干细胞和祖细胞中的 β-珠蛋白基因以治疗镰状细胞病

So Hyun Park, Ciaran M Lee, Daniel P Dever, Timothy H Davis, Joab Camarena, Waracharee Srifa, Yankai Zhang, Alireza Paikari, Alicia K Chang, Matthew H Porteus, Vivien A Sheehan, Gang Bao

Virtual resection predicts surgical outcome for drug-resistant epilepsy

虚拟切除术可预测药物难治性癫痫的手术结果

Kini, Lohith G; Bernabei, John M; Mikhail, Fadi; Hadar, Peter; Shah, Preya; Khambhati, Ankit N; Oechsel, Kelly; Archer, Ryan; Boccanfuso, Jacqueline; Conrad, Erin; Shinohara, Russell T; Stein, Joel M; Das, Sandhitsu; Kheder, Ammar; Lucas, Timothy H; Davis, Kathryn A; Bassett, Danielle S; Litt, Brian

Functional control of electrophysiological network architecture using direct neurostimulation in humans

利用直接神经刺激对人类电生理网络结构进行功能控制

Khambhati, Ankit N; Kahn, Ari E; Costantini, Julia; Ezzyat, Youssef; Solomon, Ethan A; Gross, Robert E; Jobst, Barbara C; Sheth, Sameer A; Zaghloul, Kareem A; Worrell, Gregory; Seger, Sarah; Lega, Bradley C; Weiss, Shennan; Sperling, Michael R; Gorniak, Richard; Das, Sandhitsu R; Stein, Joel M; Rizzuto, Daniel S; Kahana, Michael J; Lucas, Timothy H; Davis, Kathryn A; Tracy, Joseph I; Bassett, Danielle S

Recurring Functional Interactions Predict Network Architecture of Interictal and Ictal States in Neocortical Epilepsy

反复出现的功能性交互作用可预测新皮质癫痫发作间期和发作期的网络结构

Khambhati, Ankit N; Bassett, Danielle S; Oommen, Brian S; Chen, Stephanie H; Lucas, Timothy H; Davis, Kathryn A; Litt, Brian