日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Investigating N-arylpyrimidinamine (NAPA) compounds as early-stage inhibitors against human cytomegalovirus

研究 N-芳基嘧啶胺 (NAPA) 化合物作为人类巨细胞病毒早期抑制剂

Andrea J Parsons, Sabrina I Ophir, Thomas J Gardner, Jailene Casado Paredes, Kathryn R Stein, Steven M Kwasny, Steven C Cardinale, Matthew Torhan, Mark N Prichard, Scott H James, Kristina E Atanasoff, Narendran G-Dayanandan, Terry L Bowlin, Timothy J Opperman, Domenico Tortorella

trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo

反式翻译抑制剂与核糖体上的新位点结合,并在体内清除淋病奈瑟菌

Zachary D Aron #, Atousa Mehrani #, Eric D Hoffer #, Kristie L Connolly, Pooja Srinivas, Matthew C Torhan, John N Alumasa, Mynthia Cabrera, Divya Hosangadi, Jay S Barbor, Steven C Cardinale, Steven M Kwasny, Lucas R Morin, Michelle M Butler, Timothy J Opperman, Terry L Bowlin, Ann Jerse, Scott M Sta

Optimization of a Benzothiazole Indolene Scaffold Targeting Bacterial Cell Wall Assembly

针对细菌细胞壁组装的苯并噻唑吲哚支架的优化

Jay Chauhan, Wenbo Yu, Steven Cardinale, Timothy J Opperman, Alexander D MacKerell Jr, Steven Fletcher, Erik Ph de Leeuw

Convallatoxin-Induced Reduction of Methionine Import Effectively Inhibits Human Cytomegalovirus Infection and Replication

铃兰毒素诱导的蛋氨酸输入减少有效抑制人类巨细胞病毒感染和复制

Tobias Cohen, John D Williams, Timothy J Opperman, Roberto Sanchez, Nell S Lurain, Domenico Tortorella

Towards Development of Small Molecule Lipid II Inhibitors as Novel Antibiotics

开发小分子脂质 II 抑制剂作为新型抗生素

Jamal Chauhan, Steven Cardinale, Lei Fang, Jing Huang, Steven M Kwasny, M Ross Pennington, Kelly Basi, Robert diTargiani, Benedict R Capacio, Alexander D MacKerell Jr, Timothy J Opperman, Steven Fletcher, Erik P H de Leeuw

TAOK3 phosphorylates the methylenecyclopropane nucleoside MBX 2168 to its monophosphate

TAOK3 将亚甲基环丙烷核苷 MBX 2168 磷酸化为其单磷酸酯

Gloria Komazin-Meredith, Steven C Cardinale, Katelyn Comeau, Kevin J Magalhaes, Caroll B Hartline, John D Williams, Timothy J Opperman, Mark N Prichard, Terry L Bowlin

Structure-activity exploration of a small-molecule Lipid II inhibitor

小分子脂质 II 抑制剂的结构-活性探索

Steven Fletcher, Wenbo Yu, Jing Huang, Steven M Kwasny, Jay Chauhan, Timothy J Opperman, Alexander D MacKerell Jr, Erik P H de Leeuw

Structure-activity relationships of a novel pyranopyridine series of Gram-negative bacterial efflux pump inhibitors

新型吡喃吡啶系列革兰氏阴性细菌外排泵抑制剂的构效关系

Son T Nguyen, Steven M Kwasny, Xiaoyuan Ding, Steven C Cardinale, Courtney T McCarthy, Hong-Suk Kim, Hiroshi Nikaido, Norton P Peet, John D Williams, Terry L Bowlin, Timothy J Opperman

Characterization of a novel pyranopyridine inhibitor of the AcrAB efflux pump of Escherichia coli

大肠杆菌 AcrAB 外排泵新型吡喃吡啶抑制剂的表征

Timothy J Opperman, Steven M Kwasny, Hong-Suk Kim, Son T Nguyen, Chad Houseweart, Sanjay D'Souza, Graham C Walker, Norton P Peet, Hiroshi Nikaido, Terry L Bowlin

Static biofilm cultures of Gram-positive pathogens grown in a microtiter format used for anti-biofilm drug discovery

以微量滴定形式培养的革兰氏阳性病原体的静态生物膜培养物可用于抗生物膜药物研发

Steven M Kwasny, Timothy J Opperman