日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeted and complete genomic sequencing of the major histocompatibility complex in haplotypic form of individual heterozygous samples

对单个杂合样本的单倍型主要组织相容性复合体进行有针对性的完整基因组测序

Taishan Hu #, Timothy L Mosbruger #, Nikolaos G Tairis, Amalia Dinou, Pushkala Jayaraman, Mahdi Sarmady, Kingham Brewster, Yang Li, Tristan J Hayeck, Jamie L Duke, Dimitri S Monos

A Stat1 bound enhancer promotes Nampt expression and function within tumor associated macrophages

Stat1结合的增强子促进肿瘤相关巨噬细胞内Nampt的表达和功能

Thomas B Huffaker # ,H Atakan Ekiz # ,Cindy Barba ,Soh-Hyun Lee ,Marah C Runtsch ,Morgan C Nelson ,Kaylyn M Bauer ,William W Tang ,Timothy L Mosbruger ,James E Cox ,June L Round ,Warren P Voth ,Ryan M O'Connell

Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution

以单碱基分辨率同时对多个 RNA 修饰进行转录组范围分析

Vahid Khoddami, Archana Yerra, Timothy L Mosbruger, Aaron M Fleming, Cynthia J Burrows, Bradley R Cairns

The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment

谱系决定性转录因子SOX2和NKX2-1决定肺癌细胞命运并塑造肿瘤免疫微环境

Gurkan Mollaoglu ,Alex Jones ,Sarah J Wait ,Anandaroop Mukhopadhyay ,Sangmin Jeong ,Rahul Arya ,Soledad A Camolotto ,Timothy L Mosbruger ,Chris J Stubben ,Christopher J Conley ,Arjun Bhutkar ,Jeffery M Vahrenkamp ,Kristofer C Berrett ,Melissa H Cessna ,Thomas E Lane ,Benjamin L Witt ,Mohamed E Salama ,Jason Gertz ,Kevin B Jones ,Eric L Snyder ,Trudy G Oliver

FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer

FoxA1 和 FoxA2 驱动胃分化并抑制 NKX2-1 阴性肺癌中的鳞状细胞特性

Soledad A Camolotto ,Shrivatsav Pattabiraman # ,Timothy L Mosbruger # ,Alex Jones ,Veronika K Belova ,Grace Orstad ,Mitchell Streiff ,Lydia Salmond ,Chris Stubben ,Klaus H Kaestner ,Eric L Snyder

Active BRAF-V600E is the key player in generation of a sessile serrated polyp-specific DNA methylation profile

活性 BRAF-V600E 是产生无柄锯齿状息肉特异性 DNA 甲基化谱的关键因素

Somaye Dehghanizadeh, Vahid Khoddami, Timothy L Mosbruger, Sue S Hammoud, Kornelia Edes, Therese S Berry, Michelle Done, Wade S Samowitz, James A DiSario, Daniel G Luba, Randall W Burt, David A Jones

Reversible LSD1 inhibition with HCI-2509 induces the p53 gene expression signature and disrupts the MYCN signature in high-risk neuroblastoma cells

使用 HCI-2509 进行可逆性 LSD1 抑制可诱导高危神经母细胞瘤细胞中的 p53 基因表达特征并破坏 MYCN 特征

Sumati Gupta, Kelly Doyle, Timothy L Mosbruger, Andrew Butterfield, Alexis Weston, Allison Ast, Mohan Kaadige, Anupam Verma, Sunil Sharma

Genome-Wide CRISPR-Cas9 Screen Identifies MicroRNAs That Regulate Myeloid Leukemia Cell Growth

全基因组 CRISPR-Cas9 筛选鉴定出调控髓系白血病细胞生长的 microRNA

Jared Wallace, Ruozhen Hu, Timothy L Mosbruger, Timothy J Dahlem, W Zac Stephens, Dinesh S Rao, June L Round, Ryan M O'Connell

Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

外泌体传递的microRNA 调节对内毒素的炎症反应

Margaret Alexander, Ruozhen Hu, Marah C Runtsch, Dominique A Kagele, Timothy L Mosbruger, Tanya Tolmachova, Miguel C Seabra, June L Round, Diane M Ward, Ryan M O'Connell