The DNA methyltransferase inhibitor, guadecitabine, targets tumor-induced myelopoiesis and recovers T cell activity to slow tumor growth in combination with adoptive immunotherapy in a mouse model of breast cancer

DNA 甲基转移酶抑制剂 guadecitabine 靶向肿瘤诱导的骨髓生成，并恢复 T 细胞活性，以减缓乳腺癌小鼠模型中的肿瘤生长，并与过继免疫疗法相结合