日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

BIOM-64. ALTERATIONS IN MDM2/4-TP53 AXIS PREDICT RESPONSE TO TUMOR TREATING FIELD (TTF) THERAPY IN IDH WILD TYPE GLIOBLASTOMA

BIOM-64. MDM2/4-TP53轴的改变可预测IDH野生型胶质母细胞瘤对肿瘤电场治疗（TTF）的反应

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.4c00579
Rooney, Timothy P C; Aldred, Gregory G; Winpenny, David; Scott, Helen; Willems, Henriette M G; Voytyuk, Iryna; Clarke, Jonathan H; Boffey, Helen K; Andrews, Stephen P; Skidmore, John; Lim, Sanghee; Orusa, Ahauve; Rael, Sofia; Eckel-Passow, Jeanette; Jenkins, Robert; Ruff, Michael
P53
细胞生物学
MDM2
肿瘤
肿瘤免疫
发表日期：2025
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Selective Aurora A-TPX2 Interaction Inhibitors Have In Vivo Efficacy as Targeted Antimitotic Agents

选择性 Aurora A-TPX2 相互作用抑制剂具有体内作为靶向抗有丝分裂药物的功效

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.4c01165
Simon R Stockwell, Duncan E Scott, Gerhard Fischer, Estrella Guarino, Timothy P C Rooney, Tzu-Shean Feng, Tommaso Moschetti, Rajavel Srinivasan, Esther Alza, Alice Asteian, Claudio Dagostin, Anna Alcaide, Mathieu Rocaboy, Beata Blaszczyk, Alicia Higueruelo, Xuelu Wang, Maxim Rossmann, Trevor R Perri
信号转导
发表日期：2024
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The Identification of Potent, Selective, and Brain Penetrant PI5P4Kγ Inhibitors as In Vivo-Ready Tool Molecules

鉴定高效、选择性强且能穿透血脑屏障的PI5P4Kγ抑制剂作为体内实验用工具分子

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.2c01693
Rooney, Timothy P C; Aldred, Gregory G; Boffey, Helen K; Willems, Henriëtte M G; Edwards, Simon; Chawner, Stephen J; Scott, Duncan E; Green, Christopher; Winpenny, David; Skidmore, John; Clarke, Jonathan H; Andrews, Stephen P
血脑屏障
神经科学
发表日期：2023
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Big Things, Small Packages: An Update on Microalgae as Sustainable Sources of Nutraceutical Peptides for Promoting Cardiovascular Health

小包装，大能量：微藻作为促进心血管健康的营养保健肽可持续来源的最新进展

期刊:Global Challenges
影响因子:6.4
doi:10.1002/gch2.202200162
Ejike, Chukwunonso E C C; Ezeorba, Timothy P C; Ajah, Obinna; Udenigwe, Chibuike C
发表日期：2023
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The rational design of ARUK2007145, a dual inhibitor of the α and γ isoforms of the lipid kinase phosphatidylinositol 5-phosphate 4-kinase (PI5P4K)

ARUK2007145 的合理设计，是一种脂质激酶磷脂酰肌醇 5-磷酸 4-激酶 (PI5P4K) α 和 γ 亚型的双重抑制剂

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d3md00355h
Aldred, Gregory G; Rooney, Timothy P C; Willems, Henriette M G; Boffey, Helen K; Green, Christopher; Winpenny, David; Skidmore, John; Clarke, Jonathan H; Andrews, Stephen P
信号转导
发表日期：2023
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A Review on the Molecular Mechanisms of Action of Natural Products in Preventing Bone Diseases

天然产物预防骨骼疾病的分子作用机制综述

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms23158468
Okagu, Innocent U; Ezeorba, Timothy P C; Aguchem, Rita N; Ohanenye, Ikenna C; Aham, Emmanuel C; Okafor, Sunday N; Bollati, Carlotta; Lammi, Carmen
发表日期：2022
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Recent findings on the cellular and molecular mechanisms of action of novel food-derived antihypertensive peptides

近期关于新型食物来源抗高血压肽的细胞和分子作用机制的研究发现

期刊:Food Chemistry Molecular Sciences
影响因子:4.7
doi:10.1016/j.fochms.2022.100078
Okagu, Innocent U; Ezeorba, Timothy P C; Aham, Emmanuel C; Aguchem, Rita N; Nechi, Regina N
细胞生物学
心血管
高血压
发表日期：2022
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Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain

在设计 CREBBP 溴结构域的选择性高亲和力配体时控制分子内相互作用

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.1c00348
Michael Brand, James Clayton, Mustafa Moroglu, Matthias Schiedel, Sarah Picaud, Joseph P Bluck, Anna Skwarska, Hannah Bolland, Anthony K N Chan, Corentine M C Laurin, Amy R Scorah, Larissa See, Timothy P C Rooney, Katrina H Andrews, Oleg Fedorov, Gabriella Perell, Prakriti Kalra, Kayla B Vinh, Wilia
信号转导
发表日期：2021
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Systematic Investigation of the Permeability of Androgen Receptor PROTACs

系统研究雄激素受体PROTACs的通透性

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.0c00194
Scott, Duncan E; Rooney, Timothy P C; Bayle, Elliott D; Mirza, Tashfina; Willems, Henriette M G; Clarke, Jonathan H; Andrews, Stephen P; Skidmore, John
信号转导
免疫/内分泌
发表日期：2020
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Isoxazole-Derived Amino Acids are Bromodomain-Binding Acetyl-Lysine Mimics: Incorporation into Histone H4 Peptides and Histone H3

异噁唑衍生的氨基酸是溴结构域结合乙酰赖氨酸的类似物：可掺入组蛋白H4肽和组蛋白H3中

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.201602908
Sekirnik Née Measures, Angelina R; Hewings, David S; Theodoulou, Natalie H; Jursins, Lukass; Lewendon, Katie R; Jennings, Laura E; Rooney, Timothy P C; Heightman, Tom D; Conway, Stuart J
发表日期：2016
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