日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Neoantigen DNA vaccines are safe, feasible, and induce neoantigen-specific immune responses in triple-negative breast cancer patients

新抗原DNA疫苗安全可行,并能在三阴性乳腺癌患者中诱导新抗原特异性免疫反应。

Xiuli Zhang,S Peter Goedegebuure,Michael Y Chen,Rashmi Mishra,Felicia Zhang,Yik Yeung Yu,Kartik Singhal,Lijin Li,Feng Gao,Nancy B Myers,Tammi Vickery,Jasreet Hundal,Michael D McLellan,Mark A Sturmoski,Samuel W Kim,Ina Chen,Jesse T Davidson 4th,Narendra V Sankpal,Stephanie Myles,Rama Suresh,Cynthia X Ma,Ademuyiwa Foluso,Andrea Wang-Gillam,Sherri Davies,Ian S Hagemann,Elaine R Mardis,Obi Griffith,Malachi Griffith,Christopher A Miller,Ted H Hansen,Timothy P Fleming,Robert D Schreiber,William E Gillanders

Enhanced enrichment of extracellular vesicles for laboratory and clinical research from drop-sized blood samples

从液滴大小的血样中富集细胞外囊泡,用于实验室和临床研究。

Alexa Guerrero-Alba ,Sandhya Bansal ,Aryan N Sankpal ,Geetanjali Mitra ,Mohammad Rahman ,Ranjithkumar Ravichandran ,Christin Poulson ,Timothy P Fleming ,Michael A Smith ,Ross M Bremner ,T Mohanakumar ,Narendra V Sankpal

Cytosolic EpCAM cooperates with H-Ras to regulate epithelial to mesenchymal transition through ZEB1

细胞浆 EpCAM 与 H-Ras 协同作用,通过 ZEB1 调节上皮细胞向间质细胞的转变

Fatma A Omar, Taylor C Brown, William E Gillanders, Timothy P Fleming, Michael A Smith, Ross M Bremner, Narendra V Sankpal

Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation

优化的多表位新抗原 DNA 疫苗在临床前模型和临床转化中引发新抗原特异性免疫反应

Lijin Li, Xiuli Zhang, Xiaoli Wang, Samuel W Kim, John M Herndon, Michelle K Becker-Hapak, Beatriz M Carreno, Nancy B Myers, Mark A Sturmoski, Michael D McLellan, Christopher A Miller, Tanner M Johanns, Benjamin R Tan, Gavin P Dunn, Timothy P Fleming, Ted H Hansen, S Peter Goedegebuure, William E Gi

Cancer-associated mutations reveal a novel role for EpCAM as an inhibitor of cathepsin-L and tumor cell invasion

癌症相关突变揭示了 EpCAM 作为蛋白酶 L 和肿瘤细胞侵袭抑制剂的新作用

Narendra V Sankpal, Taylor C Brown, Timothy P Fleming, John M Herndon, Anusha A Amaravati, Allison N Loynd, William E Gillanders

Identification of Phospho-Tyrosine Targets as a Strategy for the Treatment of Esophageal Adenocarcinoma Cells

鉴定磷酸酪氨酸靶点作为治疗食管腺癌细胞的策略

John Lee, Rongbing Chen, T Mohanakumar, Ross Bremner, Sumeet Mittal, Timothy P Fleming

Development of an adenovirus vector vaccine platform for targeting dendritic cells

开发靶向树突状细胞的腺病毒载体疫苗平台

Piyush K Sharma ,Igor P Dmitriev ,Elena A Kashentseva ,Geert Raes ,Lijin Li ,Samuel W Kim ,Zhi-Hong Lu ,Jeffrey M Arbeit ,Timothy P Fleming ,Sergey A Kaliberov ,S Peter Goedegebuure ,David T Curiel ,William E Gillanders

EpCAM modulates NF-κB signaling and interleukin-8 expression in breast cancer

EpCAM 调节乳腺癌中的 NF-κB 信号和白细胞介素 8 表达

Narendra V Sankpal, Timothy P Fleming, William E Gillanders

Identification of HLA-A24-restricted CD8(+) cytotoxic T-cell epitopes derived from mammaglobin-A, a human breast cancer-associated antigen

鉴定源自人类乳腺癌相关抗原乳腺珠蛋白-A的HLA-A24限制性CD8(+)细胞毒性T细胞表位

Venkataswarup Tiriveedhi, Nayan J Sarma, Vijay Subramanian, Timothy P Fleming, William E Gillanders, Thallachallour Mohanakumar

Activator protein 1 (AP-1) contributes to EpCAM-dependent breast cancer invasion

激活蛋白 1 (AP-1) 促进 EpCAM 依赖性乳腺癌侵袭

Narendra V Sankpal, John D Mayfield, Mike W Willman, Timothy P Fleming, William E Gillanders