日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A compendium of multi-omics data illuminating host responses to lethal human virus infections

多组学数据汇编阐明了宿主对致命人类病毒感染的反应

Amie J Eisfeld #, Lindsey N Anderson #, Shufang Fan, Kevin B Walters, Peter J Halfmann, Danielle Westhoff Smith, Larissa B Thackray, Qing Tan, Amy C Sims, Vineet D Menachery, Alexandra Schäfer, Timothy P Sheahan, Adam S Cockrell, Kelly G Stratton, Bobbie-Jo M Webb-Robertson, Jennifer E Kyle, Kristin

Hepatoviruses promote very-long-chain fatty acid and sphingolipid synthesis for viral RNA replication and quasi-enveloped virus release

肝病毒促进极长链脂肪酸和鞘脂的合成,以促进病毒 RNA 复制和准包膜病毒的释放

Tomoyuki Shiota, Zhucui Li, Guan-Yuan Chen, Kevin L McKnight, Takayoshi Shirasaki, Bryan Yonish, Heyjeong Kim, Ethan J Fritch, Timothy P Sheahan, Masamichi Muramatsu, Maryna Kapustina, Craig E Cameron, You Li, Qibin Zhang, Stanley M Lemon

Advancement in Cellular Topographic and Nanoparticle Capture Imaging by High Resolution Microscopy Incorporating a Freeze-Drying and Gaseous Nitrogen-based Approach

结合冷冻干燥和气态氮方法的高分辨率显微镜在细胞拓扑和纳米颗粒捕获成像方面的进展

Kunihiro Uryu, Nadine Soplop, Timothy P Sheahan, Maria-Teresa Catanese, Chuong Huynh, John Pena, Nancy Boudreau, Irina Matei, Candia Kenific, Ayako Hashimoto, Ayuko Hoshino, Charles M Rice, David Lyden

Facile discovery of surrogate cytokine agonists

易于发现替代细胞因子激动剂

Michelle Yen ,Junming Ren ,Qingxiang Liu ,Caleb R Glassman ,Timothy P Sheahan ,Lora K Picton ,Fernando R Moreira ,Arjun Rustagi ,Kevin M Jude ,Xiang Zhao ,Catherine A Blish ,Ralph S Baric ,Leon L Su ,K Christopher Garcia

Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy

具有增强的抗 SARS-CoV-2 疗效的 Fc 工程抗体疗法

Rachel Yamin #, Andrew T Jones #, Hans-Heinrich Hoffmann, Alexandra Schäfer, Kevin S Kao, Rebecca L Francis, Timothy P Sheahan, Ralph S Baric, Charles M Rice, Jeffrey V Ravetch, Stylianos Bournazos

Cryo-EM and antisense targeting of the 28-kDa frameshift stimulation element from the SARS-CoV-2 RNA genome

SARS-CoV-2 RNA 基因组中 28 kDa 移码刺激元件的低温电子显微镜和反义靶向

Kaiming Zhang #, Ivan N Zheludev #, Rachel J Hagey #, Raphael Haslecker, Yixuan J Hou, Rachael Kretsch, Grigore D Pintilie, Ramya Rangan, Wipapat Kladwang, Shanshan Li, Marie Teng-Pei Wu, Edward A Pham, Claire Bernardin-Souibgui, Ralph S Baric, Timothy P Sheahan, Victoria D'Souza, Jeffrey S Glenn, W

Critical ACE2 Determinants of SARS-CoV-2 and Group 2B Coronavirus Infection and Replication

SARS-CoV-2 和 2B 型冠状病毒感染和复制的关键 ACE2 决定因素

Lily E Adams, Kenneth H Dinnon 3rd, Yixuan J Hou, Timothy P Sheahan, Mark T Heise, Ralph S Baric

A mechanism-based pharmacokinetic model of remdesivir leveraging interspecies scaling to simulate COVID-19 treatment in humans

基于机制的瑞德西韦药代动力学模型,利用跨物种缩放模拟人类 COVID-19 治疗

Patrick O Hanafin, Brian Jermain, Anthony J Hickey, Alexander V Kabanov, Angela Dm Kashuba, Timothy P Sheahan, Gauri G Rao

Primer ID Next-Generation Sequencing for the Analysis of a Broad Spectrum Antiviral Induced Transition Mutations and Errors Rates in a Coronavirus Genome

Primer ID 下一代测序用于分析冠状病毒基因组中广谱抗病毒诱导的转变突变和错误率

Shuntai Zhou, Collin S Hill, Michael U Clark, Timothy P Sheahan, Ralph Baric, Ronald Swanstrom

Fc-engineered antibody therapeutics with improved efficacy against COVID-19

Fc 工程抗体疗法可提高对 COVID-19 的疗效

Rachel Yamin #, Andrew T Jones #, Hans-Heinrich Hoffmann, Kevin S Kao, Rebecca L Francis, Timothy P Sheahan, Ralph S Baric, Charles M Rice, Jeffrey V Ravetch #, Stylianos Bournazos #