日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The effect of TG2-inhibitory monoclonal antibody zampilimab on tissue fibrosis in human in vitro and primate in vivo models of chronic kidney disease

TG2抑制单克隆抗体zampilimab对慢性肾脏病人体外和灵长类动物体内模型组织纤维化的影响

Linghong Huang, Helene Bon, Mabrouka Maamra, Toby Holmes, John Atkinson, Katharine Cain, Jeff Kennedy, Catherine Kettleborough, David Matthews, Breda Twomey, Jia Ni, Zhizhan Song, Philip F Watson, Timothy S Johnson

Transglutaminase 2 knockout mice are protected from bleomycin-induced lung fibrosis with preserved lung function and reduced metabolic derangements

转谷氨酰胺酶 2 基因敲除小鼠可免受博来霉素诱发的肺纤维化的影响,保持肺功能,减少代谢紊乱

Margaret A T Freeberg, Thomas H Thatcher, Sarah V Camus, Linghong Huang, John Atkinson, Wade Narrow, Jeannie Haak, Andrew M Dylag, L Ashley Cowart, Timothy S Johnson, Patricia J Sime

Transglutaminase 2: Development of therapeutic antibodies reveals four inhibitory epitopes and confirms extracellular function in fibrotic remodelling

转谷氨酰胺酶 2:治疗性抗体的开发揭示了四种抑制表位并证实了纤维化重塑中的细胞外功能

Mabrouka Maamra, Osama Mehdi Benayad, David Matthews, Catherine Kettleborough, John Atkinson, Katharine Cain, Helene Bon, Helen Brand, Michael Parkinson, Philip F Watson, Timothy S Johnson

Urinary levels of pro-fibrotic transglutaminase 2 (TG2) may help predict progression of chronic kidney disease

尿液中促纤维化转谷氨酰胺酶 2 (TG2) 的水平可能有助于预测慢性肾病的进展

Michelle Da Silva Lodge, Nick Pullen, Miguel Pereira, Timothy S Johnson

Proteomic Profiling Reveals the Transglutaminase-2 Externalization Pathway in Kidneys after Unilateral Ureteric Obstruction

蛋白质组学分析揭示单侧输尿管梗阻后肾脏的转谷氨酰胺酶-2外化途径

Giulia Furini, Nina Schroeder, Linghong Huang, David Boocock, Alessandra Scarpellini, Clare Coveney, Elisa Tonoli, Raghavendran Ramaswamy, Graham Ball, Claudia Verderio, Timothy S Johnson, Elisabetta A M Verderio

The Peroxidative Cleavage of Kaempferol Contributes to the Biosynthesis of the Benzenoid Moiety of Ubiquinone in Plants

山奈酚的过氧化裂解促进植物中泛醌苯类部分的生物合成

Eric Soubeyrand, Timothy S Johnson, Scott Latimer, Anna Block, Jeongim Kim, Thomas A Colquhoun, Eugenio Butelli, Cathie Martin, Mark A Wilson, Gilles J Basset

An immunofluorescence assay for extracellular matrix components highlights the role of epithelial cells in producing a stable, fibrillar extracellular matrix

细胞外基质成分的免疫荧光测定突出了上皮细胞在产生稳定的纤维状细胞外基质中的作用

Omar S Qureshi, Hélène Bon, Breda Twomey, Gill Holdsworth, Kirsty Ford, Marianne Bergin, Linghong Huang, Mariusz Muzylak, Louise J Healy, Vanessa Hurdowar, Timothy S Johnson

Interplay between transglutaminases and heparan sulphate in progressive renal scarring

转谷氨酰胺酶和硫酸肝素在进行性肾脏瘢痕形成中的相互作用

Izhar Burhan, Giulia Furini, Hugues Lortat-Jacob, Adeola G Atobatele, Alessandra Scarpellini, Nina Schroeder, John Atkinson, Mabrouka Maamra, Faith H Nutter, Philip Watson, Manlio Vinciguerra, Timothy S Johnson, Elisabetta A M Verderio

A crucial sequence for transglutaminase type 2 extracellular trafficking in renal tubular epithelial cells lies in its N-terminal beta-sandwich domain

肾小管上皮细胞中转谷氨酰胺酶 2 型细胞外运输的关键序列位于其 N 端 β 夹层结构域

Che-Yi Chou, Andrew J Streets, Philip F Watson, Linghong Huang, Elisabetta A M Verderio, Timothy S Johnson

Identification of early interstitial lung disease in an individual with genetic variations in ABCA3 and SFTPC

在携带 ABCA3 和 SFTPC 基因变异的个体中识别早期间质性肺病

Crossno, Peter F; Polosukhin, Vasiliy V; Blackwell, Timothy S; Johnson, Joyce E; Markin, Cheryl; Moore, Paul E; Worrell, John A; Stahlman, Mildred T; Phillips, John A 3rd; Loyd, James E; Cogan, Joy D; Lawson, William E