IRF4 variants have age-specific effects on nevus count and predispose to melanoma
IRF4 变异对痣的数量有年龄特异性影响,并易导致黑色素瘤。
期刊:American Journal of Human Genetics
影响因子:8.1
doi:10.1016/j.ajhg.2010.05.017
Duffy, David L; Iles, Mark M; Glass, Dan; Zhu, Gu; Barrett, Jennifer H; Höiom, Veronica; Zhao, Zhen Z; Sturm, Richard A; Soranzo, Nicole; Hammond, Chris; Kvaskoff, Marina; Whiteman, David C; Mangino, Massimo; Hansson, Johan; Newton-Bishop, Julia A; Bataille, Veronique; Hayward, Nicholas K; Martin, Nicholas G; Bishop, D Timothy; Spector, Timothy D; Montgomery, Grant W