日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

VCP/p97 inhibitor CB-5083 modulates muscle pathology in a mouse model of VCP inclusion body myopathy

VCP/p97 抑制剂 CB-5083 调节 VCP 包涵体肌病小鼠模型中的肌肉病理

Cheng Cheng, Lan Weiss, Henri Leinonen, Alyaa Shmara, Hong Z Yin, Timothy Ton, Annie Do, Jonathan Lee, Lac Ta, Eshanee Mohanty, Jesse Vargas, John Weiss, Krzysztof Palczewski, Virginia Kimonis0

A p97/Valosin-Containing Protein Inhibitor Drug CB-5083 Has a Potent but Reversible Off-Target Effect on Phosphodiesterase-6

含 p97/Valosin 的蛋白抑制剂药物 CB-5083 对磷酸二酯酶-6 具有强效但可逆的脱靶作用

Henri Leinonen, Cheng Cheng, Marja Pitkänen, Christopher L Sander, Jianye Zhang, Sama Saeid, Teemu Turunen, Alyaa Shmara, Lan Weiss, Lac Ta, Timothy Ton, Ari Koskelainen, Jesse D Vargas, Virginia Kimonis, Krzysztof Palczewski