日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Stability and heterogeneity in the antimicrobiota reactivity of human milk-derived immunoglobulin A

人乳源免疫球蛋白 A 的抗微生物反应性的稳定性和异质性

Chelseá B Johnson-Hence, Kathyayini P Gopalakrishna, Darren Bodkin, Kara E Coffey, Ansen H P Burr, Syed Rahman, Ali T Rai, Darryl A Abbott, Yelissa A Sosa, Justin T Tometich, Jishnu Das, Timothy W Hand

Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to Damage

膳食中过量的糖分会改变结肠细胞代谢,并损害其对损伤的增殖反应。

Ansen H P Burr ,Junyi Ji ,Kadir Ozler ,Heather L Mentrup ,Onur Eskiocak ,Brian Yueh ,Rachel Cumberland ,Ashley V Menk ,Natalie Rittenhouse ,Chris W Marshall ,Pailin Chiaranunt ,Xiaoyi Zhang ,Lauren Mullinax ,Abigail Overacre-Delgoffe ,Vaughn S Cooper ,Amanda C Poholek ,Greg M Delgoffe ,Kevin P Mollen ,Semir Beyaz ,Timothy W Hand

Group 3 innate lymphoid cells require BATF to regulate gut homeostasis in mice

第 3 组先天淋巴细胞需要 BATF 来调节小鼠的肠道稳态

Xiaopeng Wu, Achia Khatun, Moujtaba Y Kasmani, Yao Chen, Shikan Zheng, Samantha Atkinson, Christine Nguyen, Robert Burns, Elizabeth J Taparowsky, Nita H Salzman, Timothy W Hand, Weiguo Cui

A gut-oral microbiome-driven axis controls oropharyngeal candidiasis through retinoic acid

肠道口腔微生物组驱动轴通过维甲酸控制口咽念珠菌病

Felix Ey Aggor, Martinna Bertolini, Chunsheng Zhou, Tiffany C Taylor, Darryl A Abbott, Javonn Musgrove, Vincent M Bruno, Timothy W Hand, Sarah L Gaffen

Human Milk Oligosaccharides Impact Cellular and Inflammatory Gene Expression and Immune Response

母乳低聚糖影响细胞和炎症基因表达以及免疫反应

Fernanda Rosa, Ashok K Sharma, Manoj Gurung, David Casero, Katelin Matazel, Lars Bode, Christy Simecka, Ahmed A Elolimy, Patricia Tripp, Christopher Randolph, Timothy W Hand, Keith D Williams, Tanya LeRoith, Laxmi Yeruva

Mitigation of portal fibrosis and cholestatic liver disease in ANKS6-deficient livers by macrophage depletion

通过巨噬细胞耗竭减轻 ANKS6 缺陷肝脏中的门脉纤维化和胆汁淤积性肝病

Merlin Airik, Blake McCourt, Tugba Tastemel Ozturk, Amy B Huynh, Xiaoyi Zhang, Justin T Tometich, Rezan Topaloglu, Hasan Ozen, Diclehan Orhan, Kari Nejak-Bowen, Satdarshan P Monga, Timothy W Hand, Fatih Ozaltin, Rannar Airik

Metabolic support of tumour-infiltrating regulatory T cells by lactic acid

乳酸对肿瘤浸润性调节性T细胞的代谢支持

McLane J Watson ,Paolo D A Vignali ,Steven J Mullett ,Abigail E Overacre-Delgoffe ,Ronal M Peralta ,Stephanie Grebinoski ,Ashley V Menk ,Natalie L Rittenhouse ,Kristin DePeaux ,Ryan D Whetstone ,Dario A A Vignali ,Timothy W Hand ,Amanda C Poholek ,Brett M Morrison ,Jeffrey D Rothstein ,Stacy G Wendell ,Greg M Delgoffe

Microbiota-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer

微生物群特异性 T 滤泡辅助细胞驱动三级淋巴结构和针对结直肠癌的抗肿瘤免疫

Abigail E Overacre-Delgoffe, Hannah J Bumgarner, Anthony R Cillo, Ansen H P Burr, Justin T Tometich, Amrita Bhattacharjee, Tullia C Bruno, Dario A A Vignali, Timothy W Hand

Environmental enteric dysfunction induces regulatory T cells that inhibit local CD4+ T cell responses and impair oral vaccine efficacy

环境性肠道功能障碍会诱导调节性T细胞,从而抑制局部CD4+ T细胞反应并降低口服疫苗的效力。

Amrita Bhattacharjee ,Ansen H P Burr ,Abigail E Overacre-Delgoffe ,Justin T Tometich ,Deyi Yang ,Brydie R Huckestein ,Jonathan L Linehan ,Sean P Spencer ,Jason A Hall ,Oliver J Harrison ,Denise Morais da Fonseca ,Elizabeth B Norton ,Yasmine Belkaid ,Timothy W Hand

Loss of Fibroblast Growth Factor Receptor 2 (FGFR2) Leads to Defective Bladder Urothelial Regeneration after Cyclophosphamide Injury

成纤维细胞生长因子受体2 (FGFR2) 的缺失导致环磷酰胺损伤后膀胱尿路上皮再生缺陷

Sridhar T Narla ,Daniel S Bushnell ,Caitlin M Schaefer ,Mehdi Nouraie ,Justin T Tometich ,Timothy W Hand ,Carlton M Bates